Schöllnast R, Kränke B, Aberer W
Universitäts-Klinik für Dermatologie und Venerologie, Graz, Austria.
Hautarzt. 2003 Oct;54(10):970-4. doi: 10.1007/s00105-003-0585-3.
A 63-year old man developed severe perianal and palmar contact dermatitis caused by sensitization to iodopropynyl butylcarbamate in moist sanitary wipes. Iodopropynyl butylcarbamate is increasingly employed as preservative in common cosmetic formulations and moist sanitary wipes as substitute for the previously frequently used sensitizers isothiazolinones and methyldibromoglutaronitrile. The allergic potential of diverse preservatives is a serious problem for the cosmetic industry, since truly hypoallergenic preservatives are not available but products such as moist sanitary wipes in large packages definitely require some form of protection.
一名63岁男性因对湿厕纸中的碘代丙炔醇丁基氨酯过敏,出现了严重的肛周和手掌接触性皮炎。碘代丙炔醇丁基氨酯越来越多地被用作常见化妆品配方和湿厕纸中的防腐剂,以替代之前常用的致敏剂异噻唑啉酮和甲基二溴戊二腈。对于化妆品行业来说,各种防腐剂的过敏风险是一个严重问题,因为目前尚无真正低敏的防腐剂,而像大包装湿厕纸这类产品肯定需要某种形式的保护。