Abdel-Hameed A A
The Blue Nile Research and Training Institute, Wad Medani, Sudan.
Afr J Med Med Sci. 2001;30 Suppl:43-6.
This study was done to investigate malaria case management at the community level in Gezira, Sudan, which is an area of unstable malaria predominantly due to Plasmodium falciparum. Questionnaire surveys were conducted at four consecutive weekly intervals in October 1995. A sample of 400 households (3062 persons) including 200 rural and 200 urban households was studied. Use of antimalarials was assessed in terms of diagnosis, types of antimalarial used, self-medication and compliance. During the four weeks of observation, 25.1% of the rural population and 35.6% of the urban population received at least one course of antimalarial drugs. Diagnosis was confirmed microscopically in 81.7% of treated persons in the urban community and in only 34.3% those treated in the rural community. Chloroquine is the most frequently used antimalarial in both communities with notable overuse of injections in rural patients and in patients treated by paramedical health workers. Self-medication was commoner in rural than in the urban population (41.2% versus 23.9%). Compliance with the standard therapeutic doses was poorest with quinine and best with sulfadoxine/pyrimethamine. It is suggested that interventions to improve the use of antimalarials should include health education, training of health workers and dissemination of national treatment policies.
本研究旨在调查苏丹杰济拉地区社区层面的疟疾病例管理情况,该地区疟疾不稳定,主要由恶性疟原虫引起。1995年10月连续四周每周进行问卷调查。研究了包括200户农村家庭和200户城市家庭在内的400户家庭(3062人)。从诊断、使用的抗疟药类型、自我用药和依从性方面评估抗疟药的使用情况。在四周的观察期内,25.1%的农村人口和35.6%的城市人口接受了至少一个疗程的抗疟药治疗。城市社区81.7%的接受治疗者经显微镜确诊,而农村社区接受治疗者中只有34.3%经显微镜确诊。氯喹是两个社区最常用的抗疟药,农村患者和辅助医务人员治疗的患者中注射用药明显过度。农村自我用药比城市人口更普遍(41.2%对23.9%)。对标准治疗剂量的依从性,奎宁最差,磺胺多辛/乙胺嘧啶最好。建议改善抗疟药使用的干预措施应包括健康教育、卫生工作者培训和国家治疗政策的传播。