Tropical Medicine Research Institute, National Centre for Research, P.O. Box 1304, Khartoum, Sudan.
Malar J. 2009 Nov 16;8 Suppl 2(Suppl 2):S3. doi: 10.1186/1475-2875-8-S2-S3.
The global malaria situation, especially in Africa, and the problems frequently encountered in chemical control of vectors such as insecticide resistance, emphasize the urgency of research, development and implementation of new vector control technologies that are applicable at regional and local levels. The successful application of the sterile insect technique (SIT) for the control of the New World screwworm Cochliomyia hominivorax and several species of fruit flies has given impetus to the use of this method for suppression or elimination of malaria vectors in some areas of Africa including Northern State of Sudan. The research and development phase of the Northern State feasibility study has been started. Sudanese stakeholders are working side-by-side with the International Atomic Energy Agency in the activities of this important phase. Several ethical, legal and social issues associated with this approach arose during this phase of the project. They need to be seriously considered and handled with care. In this paper, these issues are described, and the current and proposed activities to overcome potential hurdles to ensure success of the project are listed.
全球疟疾形势，尤其是在非洲，以及化学防治媒介（如抗药性）方面经常遇到的问题，强调了研究、开发和实施新的、适用于区域和地方各级的病媒控制技术的紧迫性。利用不育昆虫技术（SIT）成功控制新世界螺旋蝇 Cochliomyia hominivorax 和几种实蝇，推动了在包括苏丹北方州在内的非洲一些地区使用这种方法来抑制或消灭疟疾媒介。已经开始进行北方州可行性研究的研究和开发阶段。苏丹利益攸关方与国际原子能机构并肩合作，开展这一重要阶段的活动。在项目的这个阶段出现了一些与这种方法相关的伦理、法律和社会问题。需要认真考虑并谨慎处理。本文描述了这些问题，并列出了为克服确保项目成功的潜在障碍而开展的当前和拟议活动。
