Kharb Simmi, Ghalaut Veena Singh
Department of Biochemistry, Pt. B.D. Sharma PGIMS, Rohtak.
Indian J Med Sci. 2003 Mar;57(3):105-7.
We measured lipoperoxides, as malonaldehyde (MDA) by thiobarbituric acid reaction in serum from 80 male and 120 female volunteers to establish reliable reference values and to compare possible sex- and age- related differences. In the present study women had higher MDA concentration in serum than do men (p<0.05) and older subjects had higher values (p<0.05). These age related results support the suggestions that lipid peroxidation increases with increasing age.
我们通过硫代巴比妥酸反应测定了80名男性和120名女性志愿者血清中的脂质过氧化物(以丙二醛,即MDA表示),以建立可靠的参考值,并比较可能存在的性别和年龄相关差异。在本研究中,女性血清中的MDA浓度高于男性(p<0.05),且年龄较大的受试者MDA值更高(p<0.05)。这些与年龄相关的结果支持了脂质过氧化作用随年龄增长而增加的观点。