Han Ji-Youn, Son Hyehyun, Lee Won Chul, Choi Byung Gil
Research Institute & Hospital, National Cancer Center, Goyang, Korea.
Med Oncol. 2003;20(3):265-69. doi: 10.1385/MO:20:3:265.
A gastric cancer (GC) screening program using gastrofiberscopy (GFS) or double contrast upper gastrointestinal series (UGIS), as a public policy, has been used in Korea since 1996. The aim of this study was to assess whether there have been major changes in clinicopathologic features of GC by introducing GC screening.
We reviewed the medical records of 1478 consecutive patients with GC who underwent gastrectomy between 1989 and 1999. Patients were divided into two groups: group I (before GC screening), 1989-1995 (n = 840), and group II (after GC screening), 1996-1999 (n = 638).
After employment of GC screening, the incidence of early cancer was significantly increased (21% vs 13%, p < 0.0001). During these years, the proportion of patients using GFS as the first diagnostic procedure and the relative frequency of intestinal-type GC increased significantly (63% vs 84%, 0.6 vs 1.2, respectively, p < 0.0001).
These results suggest that GC screening is effective for early detection of GC. Furthermore, the preferred screening method of GC can attribute the clinicopathologic features of GC.
自1996年起，韩国将使用纤维胃镜检查（GFS）或双重对比上消化道造影（UGIS）的胃癌（GC）筛查项目作为一项公共政策。本研究旨在评估引入GC筛查后GC的临床病理特征是否发生了重大变化。
我们回顾了1989年至1999年间连续接受胃切除术的1478例GC患者的病历。患者分为两组：第一组（GC筛查前），1989 - 1995年（n = 840），第二组（GC筛查后），1996 - 1999年（n = 638）。
采用GC筛查后，早期癌症的发病率显著增加（21%对13%，p < 0.0001）。在这些年里，将GFS作为首次诊断程序的患者比例以及肠型GC的相对频率显著增加（分别为63%对84%，0.6对1.2，p < 0.0001）。
这些结果表明GC筛查对GC的早期检测有效。此外，GC的首选筛查方法可归因于GC的临床病理特征。
