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[医学:研究中的利益冲突]

[Medicine: conflicts of interest in research].

作者信息

Fallena-Zonana Margarita, Kraus-Weisman Arnoldo

出版信息

Rev Invest Clin. 2003 May-Jun;55(3):339-46.

Abstract

A conflict of interest is a set of conditions in which professional judgment concerning a primary interest (patient's welfare, research integrity, ethics, education) tends to be influenced by a secondary interest. Among secondary interests are intellectual conflicts of interest that include the desire for faculty advancement, competition for sponsored research funding, to win prestigious research prizes, as well as financial conflicts of interest that arise when medical investigators own equity in a company that sponsors the study they conduct or when they serve as consultants to companies or are members of the company's advisory boards. Ethical conflicts of interest predominate in undeveloped countries. Known consequences of conflicts of interests include compromising health, death, minimization of adverse reactions, lower research quality, the probability to favor the sponsor's product, and delayed publication when results obtained are not the expected. Medical consciousness should be corrected to avoid moral duality that could harm both patients and medical ethics.

摘要

利益冲突是指这样一组情形

涉及主要利益(患者福祉、研究诚信、伦理、教育)的专业判断容易受到次要利益的影响。次要利益包括学术利益冲突,其中有对教师职业晋升的渴望、对赞助研究资金的竞争、赢得 prestigious 研究奖项,以及经济利益冲突,当医学研究人员在赞助其开展研究的公司拥有股权,或者担任公司顾问或公司顾问委员会成员时就会产生这种冲突。利益冲突在不发达国家中以伦理利益冲突为主。已知的利益冲突后果包括损害健康、导致死亡、将不良反应最小化、降低研究质量、偏袒赞助商产品的可能性,以及当所获结果不符合预期时延迟发表。应纠正医学意识,以避免可能损害患者和医学伦理的道德双重性。 (注:“prestigious”未翻译,因为原文中该词拼写有误,可能是“prestigious”,意为“有声望的” )

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