Hayes Don, Liles Darla K, Sorrell Vincent L
Section of General Internal Medicine, Department of Internal Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
South Med J. 2003 Aug;96(8):799-802. doi: 10.1097/01.SMJ.0000054225.89526.BD.
Primary cardiac lymphoma is a rare disease with a high mortality rate due to the advanced stage of myocardial involvement at presentation. The diagnosis is extremely difficult to make because of the rarity of the disease, variability of clinical manifestations, limited noninvasive diagnostic techniques available, and difficulties and/or delays in the use of invasive measures. The incidence of the disease is increasing, especially among immunocompromised patients, with those suffering from acquired immunodeficiency syndrome accounting for the greatest increase. We report the case of an immunocompetent 76-year-old black woman who presented with near-syncopal episodes. Transthoracic echocardiogram revealed a right atrial mass. Surgical resection was performed, and a diagnosis of large B-cell non-Hodgkin's lymphoma was made. Primary cardiac lymphoma should be considered in any patient with a cardiac mass. Prompt diagnosis and treatment of primary cardiac lymphoma is imperative for survival.
原发性心脏淋巴瘤是一种罕见疾病，由于就诊时心肌受累处于晚期，死亡率很高。由于该疾病罕见、临床表现多样、可用的非侵入性诊断技术有限以及使用侵入性措施存在困难和/或延迟，因此诊断极为困难。该疾病的发病率正在上升，尤其是在免疫功能低下的患者中，获得性免疫缺陷综合征患者的发病率上升幅度最大。我们报告了一例76岁免疫功能正常的黑人女性病例，她出现了近乎晕厥的发作。经胸超声心动图显示右心房有肿块。进行了手术切除，诊断为大B细胞非霍奇金淋巴瘤。任何有心脏肿块的患者都应考虑原发性心脏淋巴瘤。原发性心脏淋巴瘤的及时诊断和治疗对生存至关重要。
