Lin Joseph Nybo
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Int Med Case Rep J. 2010 Feb 10;3:1-6. doi: 10.2147/imcrj.s9269. Print 2010.
Cardiac involvement, as an initial presentation of malignant lymphoma is rare. We report a 42-year-old Taiwanese man with frequent syncope. Routine electrocardiography disclosed complete atrioventricular block. Before permanent pacemaker implantation was undertaken, transthoracic echocardiography revealed a solid mass infiltrating the left atrium and interatrial septum. Transesophageal echocardiography proved cardiac neoplasm with biatrial infiltration. Endomyocardial tissue biopsy was performed under angiography guide. Pathology diagnosis unraveled large B-cell lymphoma. Despite aggressive chemotherapy, the patient's condition worsened and he died 2 months later.
心脏受累作为恶性淋巴瘤的首发表现较为罕见。我们报告一名42岁的台湾男性,他频繁晕厥。常规心电图显示完全性房室传导阻滞。在进行永久性起搏器植入之前,经胸超声心动图显示一个实性肿块浸润左心房和房间隔。经食管超声心动图证实心脏肿瘤伴有双房浸润。在血管造影引导下进行了心内膜组织活检。病理诊断为大B细胞淋巴瘤。尽管进行了积极的化疗,患者的病情仍恶化,2个月后死亡。