Higaki S, Nakamura M, Yoshida I, Morohashi M
Department of Dermatology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan.
Int J Tissue React. 2003;25(2):47-50.
Secondary infections (SI) in skin lesions are common. In the present study 40 beta-hemolytic streptococci were isolated from 36 patients suffering from SI due to various skin diseases. Staphylococcus aureus coexisted with beta-hemolytic streptococci in 29 of these cases (81%), and beta-hemolytic streptococci were often associated with coagulase-negative staphylococci and gram-positive rods. Eighteen patients (50%) carried beta-hemolytic streptococci predominantly. In most cases of SI due to atopic dermatitis (AD), the predominant species was S. aureus, while in other skin diseases, S. aureus and beta-haemolytica streptococci were predominant in approximately 50% of the patients, except for SI due to tumors and viral diseases. The mean age of patients with SI and beta-hemolytic streptococci was 37 years and that of patients with SI and predominant S. aureus was 32 years. The lower mean age found for S. aureus was due to SI found in patients with AD. This study emphasizes the polymicrobial microbiology of SI.
皮肤病变中的继发性感染(SI)很常见。在本研究中,从36例因各种皮肤病导致继发性感染的患者中分离出40株β-溶血性链球菌。其中29例(81%)的金黄色葡萄球菌与β-溶血性链球菌共存,并且β-溶血性链球菌常与凝固酶阴性葡萄球菌和革兰氏阳性杆菌相关。18例患者(50%)主要携带β-溶血性链球菌。在大多数特应性皮炎(AD)所致继发性感染病例中,主要菌种是金黄色葡萄球菌,而在其他皮肤病中,除肿瘤和病毒性疾病所致继发性感染外,约50%的患者中金黄色葡萄球菌和β-溶血链球菌占主导。继发性感染合并β-溶血性链球菌患者的平均年龄为37岁,继发性感染合并主要为金黄色葡萄球菌患者的平均年龄为32岁。金黄色葡萄球菌患者平均年龄较低是由于在特应性皮炎患者中发现了继发性感染。本研究强调了继发性感染的微生物菌群多样性。