• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

MAPPFinder：利用基因本体论和GenMAPP从微阵列数据创建全局基因表达谱。

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data.

作者信息

Doniger Scott W, Salomonis Nathan, Dahlquist Kam D, Vranizan Karen, Lawlor Steven C, Conklin Bruce R

机构信息

Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.

出版信息

Genome Biol. 2003;4(1):R7. doi: 10.1186/gb-2003-4-1-r7. Epub 2003 Jan 6.

DOI:10.1186/gb-2003-4-1-r7
PMID:12540299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC151291/
Abstract

MAPPFinder is a tool that creates a global gene-expression profile across all areas of biology by integrating the annotations of the Gene Ontology (GO) Project with the free software package GenMAPP http://www.GenMAPP.org. The results are displayed in a searchable browser, allowing the user to rapidly identify GO terms with over-represented numbers of gene-expression changes. Clicking on GO terms generates GenMAPP graphical files where gene relationships can be explored, annotated, and files can be freely exchanged.

摘要

MAPPFinder是一种工具，它通过将基因本体论（GO）项目的注释与免费软件包GenMAPP（http://www.GenMAPP.org）相结合，创建涵盖生物学所有领域的全局基因表达谱。结果显示在一个可搜索的浏览器中，允许用户快速识别基因表达变化数量过多的GO术语。点击GO术语会生成GenMAPP图形文件，在其中可以探索、注释基因关系，并且文件可以自由交换。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/0feded8ee171/gb-2003-4-1-r7-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/8bd8fcb0c9ee/gb-2003-4-1-r7-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/bcbdea68d3ab/gb-2003-4-1-r7-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/0feded8ee171/gb-2003-4-1-r7-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/8bd8fcb0c9ee/gb-2003-4-1-r7-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/bcbdea68d3ab/gb-2003-4-1-r7-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c2/151291/0feded8ee171/gb-2003-4-1-r7-3.jpg

相似文献

1
MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data.MAPPFinder：利用基因本体论和GenMAPP从微阵列数据创建全局基因表达谱。
Genome Biol. 2003;4(1):R7. doi: 10.1186/gb-2003-4-1-r7. Epub 2003 Jan 6.
2
Using GenMAPP and MAPPFinder to view microarray data on biological pathways and identify global trends in the data.使用GenMAPP和MAPPFinder来查看生物途径上的微阵列数据，并识别数据中的整体趋势。
Curr Protoc Bioinformatics. 2004 May;Chapter 7:Unit 7.5. doi: 10.1002/0471250953.bi0705s05.
3
GoSurfer: a graphical interactive tool for comparative analysis of large gene sets in Gene Ontology space.GoSurfer：一种用于在基因本体论空间中对大型基因集进行比较分析的图形交互工具。
Appl Bioinformatics. 2004;3(4):261-4. doi: 10.2165/00822942-200403040-00009.
4
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data.AffyMiner：挖掘基因芯片微阵列数据中的差异表达基因和生物学知识。
BMC Bioinformatics. 2006 Dec 12;7 Suppl 4(Suppl 4):S26. doi: 10.1186/1471-2105-7-S4-S26.
5
GenMAPP 2: new features and resources for pathway analysis.基因图谱2：通路分析的新特性与资源
BMC Bioinformatics. 2007 Jun 24;8:217. doi: 10.1186/1471-2105-8-217.
6
affylmGUI: a graphical user interface for linear modeling of single channel microarray data.AffylmGUI：用于单通道微阵列数据线性建模的图形用户界面。
Bioinformatics. 2006 Apr 1;22(7):897-9. doi: 10.1093/bioinformatics/btl025. Epub 2006 Feb 2.
7
Use of GenMAPP and MAPPFinder to analyse pathways involved in chickens infected with the protozoan parasite Eimeria.使用GenMAPP和MAPPFinder分析感染原生动物寄生虫艾美耳球虫的鸡所涉及的信号通路。
BMC Proc. 2009 Jul 16;3 Suppl 4(Suppl 4):S7. doi: 10.1186/1753-6561-3-S4-S7.
8
GenePaint.org: an atlas of gene expression patterns in the mouse embryo.基因表达图谱网站（GenePaint.org）：小鼠胚胎基因表达模式图谱。
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6. doi: 10.1093/nar/gkh029.
9
ANAIS: analysis of NimbleGen arrays interface.ANAIS： NimbleGen 阵列接口分析。
Bioinformatics. 2010 Oct 1;26(19):2468-9. doi: 10.1093/bioinformatics/btq410. Epub 2010 Jul 14.
10
SEGS: search for enriched gene sets in microarray data.SEGS：在微阵列数据中搜索富集的基因集。
J Biomed Inform. 2008 Aug;41(4):588-601. doi: 10.1016/j.jbi.2007.12.001. Epub 2007 Dec 15.

引用本文的文献

1
Sustainable software development in science - insights from 20 years of Vanted.科学领域的可持续软件开发——来自20年Vanted的见解。
J Integr Bioinform. 2025 Jul 1;22(1). doi: 10.1515/jib-2025-0007. eCollection 2025 Mar 1.
2
Transcriptomic Module Discovery of Diarrhea-Predominant Irritable Bowel Syndrome: A Causal Network Inference Approach.腹泻型肠易激综合征的转录组模块发现：一种因果网络推断方法。
Int J Mol Sci. 2024 Aug 28;25(17):9322. doi: 10.3390/ijms25179322.
3
Comprehensive Biosafety Profile of Carbomer-Based Hydrogel Formulations Incorporating Phosphorus Derivatives.

本文引用的文献

1
Pathway Processor: a tool for integrating whole-genome expression results into metabolic networks.通路处理器：一种将全基因组表达结果整合到代谢网络中的工具。
Genome Res. 2002 Jul;12(7):1121-6. doi: 10.1101/gr.226602.
2
Visualizing metabolic activity on a genome-wide scale.在全基因组范围内可视化代谢活性。
Bioinformatics. 2002 Jun;18(6):813-8. doi: 10.1093/bioinformatics/18.6.813.
3
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster.衰老和热量限制的黑腹果蝇的全基因组转录谱
含磷衍生物的卡波姆基水凝胶制剂的综合生物安全性概况
Gels. 2024 Jul 18;10(7):477. doi: 10.3390/gels10070477.
4
Treadmill training impacts the skeletal muscle molecular clock after ischemia stroke in rats.跑步机训练对大鼠缺血性中风后的骨骼肌分子时钟有影响。
Heliyon. 2024 Mar 12;10(6):e27430. doi: 10.1016/j.heliyon.2024.e27430. eCollection 2024 Mar 30.
5
Exploring pathway interactions to detect molecular mechanisms of disease: 22q11.2 deletion syndrome.探索途径相互作用以检测疾病的分子机制：22q11.2 缺失综合征。
Orphanet J Rare Dis. 2023 Oct 24;18(1):335. doi: 10.1186/s13023-023-02953-6.
6
TLSEA: a tool for lncRNA set enrichment analysis based on multi-source heterogeneous information fusion.TLSEA：一种基于多源异构信息融合的lncRNA集富集分析工具。
Front Genet. 2023 May 2;14:1181391. doi: 10.3389/fgene.2023.1181391. eCollection 2023.
7
Influence of Scaffold Microarchitecture on Angiogenesis and Regulation of Cell Differentiation during the Early Phase of Bone Healing: A Transcriptomics and Histological Analysis.支架微结构对骨愈合早期血管生成和细胞分化调控的影响：转录组学和组织学分析。
Int J Mol Sci. 2023 Mar 22;24(6):6000. doi: 10.3390/ijms24066000.
8
Arbitrary Ca regulation for endothelial nitric oxide, NFAT and NF-κB activities by an optogenetic approach.通过光遗传学方法对内皮型一氧化氮、活化T细胞核因子和核因子κB活性进行任意钙调节。
Front Pharmacol. 2023 Jan 10;13:1076116. doi: 10.3389/fphar.2022.1076116. eCollection 2022.
9
Gene function prediction based on combining gene ontology hierarchy with multi-instance multi-label learning.基于基因本体层次结构与多实例多标签学习相结合的基因功能预测
RSC Adv. 2018 Aug 10;8(50):28503-28509. doi: 10.1039/c8ra05122d. eCollection 2018 Aug 7.
10
Interacting Effects of Sea Louse () Infection and Formalin-Killed on Atlantic Salmon Skin Transcriptome.海虱感染与福尔马林灭活对大西洋鲑鱼皮转录组的互作效应。
Front Immunol. 2022 Mar 24;13:804987. doi: 10.3389/fimmu.2022.804987. eCollection 2022.
Curr Biol. 2002 Apr 30;12(9):712-23. doi: 10.1016/s0960-9822(02)00808-4.
4
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways.GenMAPP，一种用于查看和分析生物途径上微阵列数据的新工具。
Nat Genet. 2002 May;31(1):19-20. doi: 10.1038/ng0502-19.
5
Elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor alpha knockout embryos.升高的转化生长因子β2增强细胞凋亡，并导致维甲酸X受体α基因敲除胚胎的流出道和主动脉囊发育异常。
Development. 2002 Feb;129(3):733-46. doi: 10.1242/dev.129.3.733.
6
The Mouse Genome Database (MGD): the model organism database for the laboratory mouse.小鼠基因组数据库（MGD）：实验小鼠的模式生物数据库。
Nucleic Acids Res. 2002 Jan 1;30(1):113-5. doi: 10.1093/nar/30.1.113.
7
Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO).酵母基因组数据库（SGD）使用基因本体论（GO）提供二级基因注释。
Nucleic Acids Res. 2002 Jan 1;30(1):69-72. doi: 10.1093/nar/30.1.69.
8
The MetaCyc Database.代谢途径与酶数据库
Nucleic Acids Res. 2002 Jan 1;30(1):59-61. doi: 10.1093/nar/30.1.59.
9
Creating the gene ontology resource: design and implementation.创建基因本体资源：设计与实现
Genome Res. 2001 Aug;11(8):1425-33. doi: 10.1101/gr.180801.
10
Genome-scale Gene Expression Analysis and Pathway Reconstruction in KEGG.KEGG中的全基因组规模基因表达分析与通路重建
Genome Inform Ser Workshop Genome Inform. 1999;10:94-103.