复方新诺明敏感、耐甲氧西林金黄色葡萄球菌，以色列，1988 - 1997年
Co-trimoxazole-sensitive, methicillin-resistant Staphylococcus aureus, Israel, 1988-1997.
作者信息
Bishara Jihad, Pitlik Silvio, Samra Zmira, Levy Itzhak, Paul Mical, Leibovici Leonard
机构信息
Department of Internal Medicine C, Rabin Medical Center, Beilinson Campus, Petach-Tikvah, Israel.
出版信息
Emerg Infect Dis. 2003 Sep;9(9):1168-9. doi: 10.3201/eid0909.020666.
Among bloodstream methicillin-resistant Staphylococcus aureus (MRSA) isolates from adult patients in a single hospital, susceptibility to co-trimoxazole increased progressively from 31% in 1988 to 92% in 1997 (p<0.0001). If also observed in other institutions, these findings should encourage the performance of a clinical trial of sufficient size to compare co-trimoxazole to vancomycin in treating MRSA infections.
在一家医院成年患者的血流耐甲氧西林金黄色葡萄球菌（MRSA）分离株中，对复方新诺明的敏感性从1988年的31%逐渐升至1997年的92%（p<0.0001）。如果在其他机构也观察到这些结果，这些发现应促使开展一项规模足够大的临床试验，以比较复方新诺明与万古霉素治疗MRSA感染的效果。
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