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码头的痘疹:澳大利亚监狱系统中的水痘爆发

Pox in the docks: varicella outbreak in an Australian prison system.

作者信息

Levy Michael H, Quilty Simon, Young Lorraine C, Hunt Wayne, Matthews Richard, Robertson Peter W

机构信息

Corrections Health Service, Long Bay Prison Hospital, Matraville, NSW 2036, Australia.

出版信息

Public Health. 2003 Nov;117(6):446-51. doi: 10.1016/S0033-3506(03)00138-0.

Abstract

OBJECTIVES

  1. Describe an outbreak of varicella in a prison system. 2. Highlight the risks of disease transmission within the prison environment. 3. Promote infection control guidelines for high-risk sub-groups within the prison system, including the application of quarantine.

SETTING

Four prisons, one prison hospital, the prison transport system, one courthouse.

MAIN OUTCOME MEASURES

Number of cases of varicella infection; reported varicella immunity status of cases and contacts; immunity status of known HIV antibody positive inmates.

RESULTS

Five cases of chickenpox were identified. There were 23 contacts of the Index Case occurring during transport between prison and court and whilst being held in the court holding cells. Two of these contacts developed chickenpox despite having given a prior history of infection. There were over 300 inmates exposed to varicella zoster virus (VZV) during the outbreak, including one HIV antibody positive inmate who had serologically confirmed immunity. This inmate developed shingles following exposure to VZV from one of the cases.

CONCLUSIONS

There is an elevated risk of respiratory transmission of infections such as chickenpox in prisons. Clear guidelines should be in place to protect HIV antibody positive people, pregnant women, and others who are at increased risk of complications from such infections. In the case of varicella, all inmates and staff without documented immunity should be screened to determine immunity, and if non-immune, should be offered VZV vaccination. Every effort should be made to prevent HIV antibody positive inmates being exposed to varicella, regardless of their varicella immunity status. If an HIV antibody positive inmate, who is known to be non-immune is exposed to varicella, Varicella Zoster immunoglobulin should be given within 96 h.

摘要

目的

  1. 描述监狱系统内水痘的一次暴发。2. 强调监狱环境中疾病传播的风险。3. 推广针对监狱系统内高危亚组的感染控制指南,包括检疫措施的应用。

背景

四座监狱、一家监狱医院、监狱运输系统、一家法院。

主要观察指标

水痘感染病例数;病例及接触者报告的水痘免疫状况;已知HIV抗体阳性囚犯的免疫状况。

结果

确诊5例水痘病例。首例病例有23名接触者,这些接触发生在监狱与法院之间的转运过程中以及被关押在法院候审室期间。其中两名接触者尽管曾有感染史,但仍患上了水痘。疫情暴发期间,有300多名囚犯接触了水痘带状疱疹病毒(VZV),包括一名经血清学确认具有免疫力的HIV抗体阳性囚犯。该囚犯在接触其中一例VZV后患上了带状疱疹。

结论

监狱中水痘等感染通过呼吸道传播的风险较高。应制定明确的指南以保护HIV抗体阳性者、孕妇及其他感染并发症风险增加的人群。对于水痘,应筛查所有无免疫记录的囚犯和工作人员以确定其免疫状况,若未免疫,应提供VZV疫苗接种。应尽一切努力防止HIV抗体阳性囚犯接触水痘,无论其水痘免疫状况如何。如果已知一名未免疫的HIV抗体阳性囚犯接触了水痘,应在96小时内给予水痘带状疱疹免疫球蛋白。

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