结膜组织胞浆菌肉芽肿
Histoplasma granuloma of the conjunctiva.
作者信息
Knox David L, O'Brien Terrence P, Green W Richard
机构信息
Eye Pathology Laboratory, Wilmer Institute and Department of Pathology, Johns Hopkins Medical Institution, 600 North Wolfe Street, Baltimore, MD 21287-9248, USA.
出版信息
Ophthalmology. 2003 Oct;110(10):2051-3. doi: 10.1016/S0161-6420(03)00665-1.
PURPOSE
To describe the clinical and pathologic features of a conjunctival granuloma resulting from Histoplasma capsulatum.
DESIGN
Clinicopathologic case report.
METHODS
Surgical excision of conjunctival lesion, histopathologic study with special stains, and a fluorescent antibody technique.
RESULTS
A conjunctiva granuloma was found to contain microorganisms, compatible with H. capsulatum, confirmed by a fluorescent antibody technique. The conjunctiva returned to normal.
CONCLUSIONS
A focal granuloma of the conjunctiva contained H. capsulatum in a patient whose recent symptoms suggested primary infection. The conjunctival lesion was similar to mucocutaneous lesions seen in patients with systemic histoplasmosis.
目的
描述由荚膜组织胞浆菌引起的结膜肉芽肿的临床和病理特征。
设计
临床病理病例报告。
方法
手术切除结膜病变组织，进行特殊染色的组织病理学研究以及荧光抗体技术检测。
结果
通过荧光抗体技术证实，结膜肉芽肿中发现了与荚膜组织胞浆菌相符的微生物。结膜恢复正常。
结论
一名近期症状提示原发性感染的患者结膜局灶性肉芽肿中含有荚膜组织胞浆菌。结膜病变与系统性组织胞浆菌病患者的黏膜皮肤病变相似。
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