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一名免疫功能低下患者发生播散性组织胞浆菌病并累及结膜。

Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient.

作者信息

Shirali Arun, Kini Jyoti, Vupputuri Anjith, Kuruvila Maria, Prabhu M Venkatraya

机构信息

Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

出版信息

Indian J Sex Transm Dis AIDS. 2010 Jan;31(1):35-8. doi: 10.4103/0253-7184.68999.

DOI:10.4103/0253-7184.68999
PMID:21808435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3140147/
Abstract

We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

摘要

我们报告一例来自印度南部的37岁男性获得性免疫缺陷综合征患者的播散性组织胞浆菌病。该患者表现为高热、咳嗽、结膜结节和丘疹结节性色素沉着性皮肤损害。皮肤损害和结膜结节的组织学检查显示巨噬细胞内有大量胞内高碘酸希夫染色阳性的圆形酵母细胞。骨髓穿刺证实为播散性组织胞浆菌病。患者开始使用两性霉素B治疗后反应显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faa/3140147/46d1a72f7e67/IJSTD-31-35-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faa/3140147/46d1a72f7e67/IJSTD-31-35-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faa/3140147/46d1a72f7e67/IJSTD-31-35-g003.jpg

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Indian J Dermatol Venereol Leprol. 2009 Mar-Apr;75(2):173-6. doi: 10.4103/0378-6323.48665.
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