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子痫前期的母胎混合淋巴细胞反应性

Maternal-fetal mixed lymphocyte reactivity in pre-eclampsia.

作者信息

Curzen P, Jones E, Gaugas J M

出版信息

Br J Exp Pathol. 1977 Oct;58(5):500-3.

Abstract

Two-way mixed lymphocyte reactivity (2-way-MLR) between maternal and fetal lymphocytes in vitro, and one-way mixed lymphocyte reactivity (1-way-MLR) of maternal lymphocytes (responders) to stimulation by mitomycin-treated fetal lymphocytes (stimulators), were investigated in normal and pre-eclamptic pregnancies. No relationship was observed between pre-eclampsia and the 2-way-MLR. The 1-way-MLR was lowest in normal pregnancy, higher in mild pre-eclampsia, and highest in severe pre-eclampsia, although none of these differences were statistically significant.

摘要

在正常妊娠和子痫前期妊娠中,研究了母体和胎儿淋巴细胞之间的双向混合淋巴细胞反应性(2-way-MLR),以及母体淋巴细胞(反应细胞)对经丝裂霉素处理的胎儿淋巴细胞(刺激细胞)刺激的单向混合淋巴细胞反应性(1-way-MLR)。未观察到子痫前期与2-way-MLR之间存在关联。1-way-MLR在正常妊娠中最低,在轻度子痫前期中较高,在重度子痫前期中最高,尽管这些差异均无统计学意义。

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本文引用的文献

7
The immunological reactivity of maternal lymphocytes in pregnancy.孕期母体淋巴细胞的免疫反应性。
J Obstet Gynaecol Br Commonw. 1973 Jul;80(7):608-10. doi: 10.1111/j.1471-0528.1973.tb16034.x.
8
Suppressive activity of pregnancy plasma on the mixed lymphocyte reaction.妊娠血浆对混合淋巴细胞反应的抑制活性。
J Obstet Gynaecol Br Commonw. 1973 Jul;80(7):603-7. doi: 10.1111/j.1471-0528.1973.tb16033.x.

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