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Soy, garlic, and ginkgo biloba: their potential role in cardiovascular disease prevention and treatment.

作者信息

Gardner Christopher D, Messina Mark, Lawson Larry D, Farquhar John W

机构信息

Stanford Center for Research in Disease Prevention, Stanford University Medical School, 730 Welch Road, Suite B, Palo Alto, CA 94304-1583, USA.

出版信息

Curr Atheroscler Rep. 2003 Nov;5(6):468-75. doi: 10.1007/s11883-003-0037-7.

DOI:10.1007/s11883-003-0037-7
PMID:14525680
Abstract

There are hundreds of foods, nutrients, herbs, and botanicals that have "bioactive" constituents with potential human health benefits. Three of these are discussed in this review: soy, garlic, and ginkgo biloba. Each of these three choices involves an ingestible item composed of a complex mixture of bioactive agents. For each of these three, there is a large and growing body of research suggesting potential cardiovascular health benefits. And for each there is at least some level of disagreement or controversy. The focus of this review is on results from recent human clinical trials.

摘要

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Does Ginkgo biloba reduce the risk of cardiovascular events?银杏叶能否降低心血管事件的风险?
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本文引用的文献

1
Dietary soy isoflavones inhibit activation of rat platelets.
J Nutr Biochem. 1999 Jul;10(7):421-6. doi: 10.1016/s0955-2863(99)00023-6.
2
Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women.含异黄酮的大豆蛋白对健康绝经后女性的内皮功能有积极影响,且这种影响独立于脂质和抗氧化作用。
Am J Clin Nutr. 2003 Jul;78(1):123-30. doi: 10.1093/ajcn/78.1.123.
3
Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women.异黄酮可降低动脉僵硬度:一项针对男性和绝经后女性的安慰剂对照研究。
Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1066-71. doi: 10.1161/01.ATV.0000072967.97296.4A. Epub 2003 Apr 24.
4
Effects of soy protein on endothelium-dependent vasodilatation and lipid profile in postmenopausal women with mild hypercholesterolemia.大豆蛋白对轻度高胆固醇血症绝经后女性内皮依赖性血管舒张及血脂谱的影响。
Clin Invest Med. 2003 Feb;26(1):20-6.
5
Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.摄入银杏叶提取物对健康受试者和2型糖尿病患者血小板聚集及尿类前列腺素排泄的影响。
Thromb Res. 2002 Nov 1;108(2-3):151-60. doi: 10.1016/s0049-3848(02)00394-8.
6
Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations.药物质量对银杏制剂中活性成分生物利用度的影响。
J Pharm Pharmacol. 2002 Nov;54(11):1507-14. doi: 10.1211/002235702199.
7
A dietary portfolio approach to cholesterol reduction: combined effects of plant sterols, vegetable proteins, and viscous fibers in hypercholesterolemia.一种降低胆固醇的膳食组合方法:植物甾醇、植物蛋白和粘性纤维对高胆固醇血症的联合作用。
Metabolism. 2002 Dec;51(12):1596-604. doi: 10.1053/meta.2002.35578.
8
The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones.代谢物雌马酚的临床重要性——大豆及其异黄酮有效性的线索
J Nutr. 2002 Dec;132(12):3577-84. doi: 10.1093/jn/132.12.3577.
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Effects of a Ginkgo biloba extract on forearm haemodynamics in healthy volunteers.银杏叶提取物对健康志愿者前臂血流动力学的影响。
Clin Physiol Funct Imaging. 2002 Nov;22(6):375-8. doi: 10.1046/j.1475-097x.2002.00445.x.
10
Lipoprotein response to diets high in soy or animal protein with and without isoflavones in moderately hypercholesterolemic subjects.中度高胆固醇血症患者对含或不含异黄酮的高大豆蛋白或动物蛋白饮食的脂蛋白反应。
Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1852-8. doi: 10.1161/01.atv.0000033513.18431.a1.