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[人用破伤风抗毒素再次免疫后血液淋巴细胞群体电荷的变化]

[Changes in the electric charge of blood lymphocyte populations after secondary immunization with tetanus antitoxin in man].

作者信息

Chollet P, Chassagne J, Vuillaume C, Bidet J M, Sauvezie B, Plagne R

出版信息

C R Seances Soc Biol Fil. 1977;171(4):791-5.

PMID:145281
Abstract

The electrophoretic mobility of circulating lymphocytes has been studied in normal human subjects after immunization by tetanus toxoid. The mean migration speed was shown to increase, particularly two and three days after secondary immunization. This increase appeared to be due to the elevation of percentage of T cells migrating at 1.20 and 1.35 micrometer. sec.-1v.-1 cm. (active rosettes-forming cells), with a decrease of the percentage of B cells and T lymphocytes migrating at 1.10 micrometer. sec.-1v.-1 cm. The return to the anterior status was observed between day 4 and 8 after immunization.

摘要

在破伤风类毒素免疫后,对正常人体受试者循环淋巴细胞的电泳迁移率进行了研究。结果显示,平均迁移速度增加,尤其是在再次免疫后的第二天和第三天。这种增加似乎是由于迁移速度为1.20和1.35微米·秒⁻¹·伏⁻¹·厘米的T细胞百分比升高(活性玫瑰花结形成细胞),而迁移速度为1.10微米·秒⁻¹·伏⁻¹·厘米的B细胞和T淋巴细胞百分比下降。免疫后第4天至第8天观察到恢复到先前状态。

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