Astin John A, Berman Brian M, Bausell Barker, Lee Wen-Lin, Hochberg Marc, Forys Kelly L
California Pacific Medical Center Research Institute, 2300 California Street, Room 207, San Francisco, CA 94115, USA.
J Rheumatol. 2003 Oct;30(10):2257-62.
To test the short and longterm benefits of an 8 week mind-body intervention that combined training in mindfulness meditation with Qigong movement therapy for individuals with fibromyalgia syndrome (FM).
A total of 128 individuals with FM were randomly assigned to the mind-body training program or an education support group that served as the control. Outcome measures were pain, disability (Fibromyalgia Impact Questionnaire), depression, myalgic score (number and severity of tender points), 6 minute walk time, and coping strategies, which were assessed at baseline and at 8, 16, and 24 weeks.
Both groups registered statistically significant improvements across time for the Fibromyalgia Impact Questionnaire, Total Myalgic Score, Pain, and Depression, and no improvement in the number of feet traversed in the 6 minute walk. However, there was no difference in either the rate or magnitude of these changes between the mind-body training group and the education control group. Salutary changes occurring by the eighth week (which corresponded to the end of the mind-body and education control group sessions) were largely maintained by both groups throughout the 6 month followup period.
While both groups showed improvement on a number of outcome variables, there was no evidence that the multimodal mind-body intervention for FM was superior to education and support as a treatment option. Additional randomized controlled trials are needed before interventions of this kind can be recommended for treatment of FM.
测试一项为期8周的身心干预措施对纤维肌痛综合征（FM）患者的短期和长期益处，该干预措施将正念冥想训练与气功运动疗法相结合。
总共128名FM患者被随机分配到身心训练项目组或作为对照组的教育支持组。结果指标包括疼痛、残疾程度（纤维肌痛影响问卷）、抑郁、肌痛评分（压痛点数量和严重程度）、6分钟步行时间以及应对策略，在基线、第8周、第16周和第24周进行评估。
两组在纤维肌痛影响问卷、总肌痛评分、疼痛和抑郁方面随时间推移均有统计学意义上的显著改善，而6分钟步行的步数没有改善。然而，身心训练组和教育对照组在这些变化的速率或幅度上没有差异。到第8周（相当于身心训练组和教育对照组课程结束时）出现的有益变化在6个月的随访期内两组基本都保持了下来。
虽然两组在多个结果变量上都有改善，但没有证据表明针对FM的多模式身心干预作为一种治疗选择优于教育和支持。在推荐此类干预措施用于FM治疗之前，还需要更多的随机对照试验。
