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青蒿素背后跨越四千多年的故事——一种源自传统中草药的神奇抗疟药物。

An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb.

作者信息

Li Ying, Wu Yu-Lin

机构信息

Shanghai Institute of Material Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.

出版信息

Curr Med Chem. 2003 Nov;10(21):2197-230. doi: 10.2174/0929867033456710.

DOI:10.2174/0929867033456710
PMID:14529339
Abstract

This article reviews the discovery and the further studies on qinghaosu and its derivatives or analogs over the last decades in the fields of medicinal chemistry and some pharmacology research, with an emphasis on the progress achieved in China.

摘要

本文综述了过去几十年来在药物化学和一些药理学研究领域中关于青蒿素及其衍生物或类似物的发现和进一步研究，重点介绍了中国所取得的进展。

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An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb.青蒿素背后跨越四千多年的故事——一种源自传统中草药的神奇抗疟药物。
Curr Med Chem. 2003 Nov;10(21):2197-230. doi: 10.2174/0929867033456710.
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Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers.青蒿素衍生的、化学性质稳定的三氧杂环乙烷二聚体的抗疟、抗增殖和抗肿瘤活性。
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