Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China.
Acta Pharmacol Sin. 2012 Sep;33(9):1141-6. doi: 10.1038/aps.2012.104. Epub 2012 Aug 27.
Qinghaosu and its derivatives are widely used in the world as a new generation of antimalarial drug. Up to now, some important progresses of Qinghaosu research have been made, including synthesis of new qinghaosu derivatives and analogs, investigation on their bioactivities and mode of actions. The present review briefly describes these efforts made by researchers in China, particularly in this Institute.
青蒿素及其衍生物在世界范围内广泛用作新一代抗疟药物。到目前为止,青蒿素的研究已经取得了一些重要进展,包括新的青蒿素衍生物和类似物的合成、它们的生物活性和作用模式的研究。本文简要描述了中国研究人员,特别是本研究所的研究人员在这方面所做的努力。