Udani Vrajesh, Udani Soonu, Merani Rohan, Bavdekar Manisha
Department of Pediatrics, P.D. Hinduja Hospital and Medical Research Center, Veer Savarkar Marg, Mumbai 400 016, India.
Indian Pediatr. 2003 Sep;40(9):870-3.
Infantile hydrocephalus due to unrecognized neonatal-onset meningitis/ventriculitis, was studied retrospectively using 1991-1998 chart review. Seventy two patients with hydrocephalus were reviewed. Thirteen infants had hydrocephalus associated with active meningitis/ventriculitis which had remained unrecognized. Active meningitis/ventriculitis was confirmed by the finding of an abnormal lumbar and ventricular CSF with or without positive culture. All had perinatal risk factors and 10/13 had been given antibiotics in the postnatal period. 6/13 infants appeared to be well. The most common presentation was increasing head size. All lumbar and ventricular CSFs were abnormal and 10/13 had positive cultures as well. Imaging revealed hydrocephalus in all. The infants were treated with antibiotics for a mean of 32.8 days before VP shunting. 7/11 were severely disabled. Unrecognized active meningitis/ventriculitis is an important cause of infantile hydrocephalus.
通过回顾1991 - 1998年的病历，对因未被识别的新生儿期脑膜炎/脑室炎导致的婴儿脑积水进行了研究。对72例脑积水患者进行了回顾。13例婴儿的脑积水与未被识别的活动性脑膜炎/脑室炎相关。通过腰椎和脑室脑脊液异常（无论培养结果是否为阳性）确诊为活动性脑膜炎/脑室炎。所有患儿均有围产期危险因素，13例中有10例在出生后接受了抗生素治疗。13例中有6例婴儿外表看似健康。最常见的表现是头围增大。所有腰椎和脑室脑脊液均异常，13例中有10例培养结果也为阳性。影像学检查显示所有患儿均有脑积水。在进行脑室腹腔分流术之前，这些婴儿平均接受了32.8天的抗生素治疗。11例中有7例严重残疾。未被识别的活动性脑膜炎/脑室炎是婴儿脑积水的一个重要原因。
