Gasser Theo, Rousson Valentin, Schreiter Gasser Ursula
Institute for Social and Preventive Medicine, University of Zurich, Switzerland.
J Clin Neurophysiol. 2003 Jul-Aug;20(4):273-82. doi: 10.1097/00004691-200307000-00007.
SUMMARY This study deals with the quantitative EEG (QEEG) of children attending schools for the mentally retarded and learning disabled. Questions are in which way do the EEGs of these children differ from normal development and whether deviations are restricted to a subgroup of children. The topographic distribution of EEG power is of particular interest. Based on a sample of n = 158 normal children, age-standardized values of absolute power (delta, theta, alpha 1, alpha 2, beta 1, beta 2 at F4, F3, C4, C3, CZ, PZ, O2, O1) and of coherence are computed for all children. The topographic distribution is assessed by analysis of variance (ANOVA) and by a principal component approach. The EEG of children with educational problems differs substantially from normal development in the slow bands and differs less in the fast bands. Deviations affect a subgroup of children, mainly children attending a school for the mentally retarded. Topographic distribution is an important factor in all bands. Coherence analysis leads to rather weak results that lack a clear interpretation. The QEEG is useful for understanding neurophysiological development in children with educational problems as a group more than individually. Parameters of topographic distribution provide strong additional information to power itself.
摘要 本研究探讨了就读于智障及学习障碍儿童学校的儿童的定量脑电图（QEEG）。问题在于这些儿童的脑电图与正常发育情况有何不同，以及偏差是否仅限于儿童亚组。脑电图功率的地形分布特别令人感兴趣。基于n = 158名正常儿童的样本，计算了所有儿童的绝对功率（F4、F3、C4、C3、CZ、PZ、O2、O1处的δ波、θ波、α1波、α2波、β1波、β2波）和相干性的年龄标准化值。通过方差分析（ANOVA）和主成分分析法评估地形分布。有教育问题的儿童的脑电图在慢波频段与正常发育有很大差异，在快波频段差异较小。偏差影响一个儿童亚组，主要是就读于智障儿童学校的儿童。地形分布在所有频段都是一个重要因素。相干性分析得出的结果相当微弱，缺乏明确的解释。定量脑电图对于从群体而非个体角度理解有教育问题的儿童的神经生理发育很有用。地形分布参数为功率本身提供了强有力的额外信息。
