从牛大力茎皮中鉴定出一种抗炎成分。
Identification of an anti-inflammatory principle from the stem bark of Millettia versicolor.
作者信息
Fotsing Maurice Tagatsing, Yankep Emmanuel, Njamen Dieudonné, Fomum Z Tanee, Nyasse Barthelemy, Bodo B, Recio M Carmen, Giner Rosa M, Ríos José-Luis
机构信息
Department of Organic Chemistry, University of Yaounde 1, Yaounde, Cameroon.
出版信息
Planta Med. 2003 Aug;69(8):767-70. doi: 10.1055/s-2003-42794.
The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of 2-acetyl-7-methoxynaphtho[2,3- b]furan-4,9-quinone (1) along with two known quinones. Pharmacological data demonstrate that compound 1 has relevant anti-inflammatory properties whereas the other two isolated compounds do not.
变色崖豆藤（豆科）茎皮甲醇提取物的二氯甲烷可溶部分已被证明具有抗炎活性。对该提取物进行色谱分离并随后分析光谱数据，从而分离并鉴定出2-乙酰基-7-甲氧基萘并[2,3-b]呋喃-4,9-醌（1）以及两种已知的醌类化合物。药理数据表明，化合物1具有相关的抗炎特性，而另外两种分离出的化合物则没有。
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