Wadsworth Emma J K, Moss Susanna C, Simpson Sharon A, Smith Andrew P
Centre for Occupational and Health Psychology, Cardiff University, 63 Park Place, Cardiff CF10 3AS, UK.
Hum Psychopharmacol. 2003 Oct;18(7):535-40. doi: 10.1002/hup.516.
Psychotropic medication may impair psychomotor and cognitive function, and so increase accident susceptibility. However, few studies examine any association in the framework of other demographic, health and occupational factors.
To examine the relationship between sleeping tablets and antidepressants, and accidents, minor injuries and cognitive failures.
Postal questionnaire study of 3111 individuals who participated in an earlier phase of the Bristol Stress and Health Study.
Sleeping tablet use was associated with accidents, minor injuries and cognitive failures both at work and outside work. Antidepressant use was associated with accidents and cognitive failures both at work and outside work. Adjusting for health, demographic and occupational factors explained many of these associations, but sleeping tablet use was independently associated with accidents (both at work and outside work), and antidepressant use with cognitive failures (outside work).
Antidepressant and sleeping tablet use were apparently associated with accidents, minor injuries and cognitive failures. Although most of the associations could be accounted for by other factors the results suggested links between sleeping tablet use and accidents, and between antidepressant use and cognitive failures.
精神药物可能会损害精神运动和认知功能，从而增加事故易发性。然而，很少有研究在其他人口统计学、健康和职业因素的框架内考察这种关联。
研究安眠药和抗抑郁药与事故、轻伤及认知失误之间的关系。
对参与布里斯托尔压力与健康研究早期阶段的3111名个体进行邮寄问卷调查。
服用安眠药与工作中和工作外的事故、轻伤及认知失误相关。服用抗抑郁药与工作中和工作外的事故及认知失误相关。对健康、人口统计学和职业因素进行调整后解释了其中许多关联，但服用安眠药与事故（工作中和工作外）独立相关，服用抗抑郁药与认知失误（工作外）独立相关。
服用抗抑郁药和安眠药显然与事故、轻伤及认知失误有关。尽管大多数关联可以由其他因素解释，但结果表明服用安眠药与事故之间以及服用抗抑郁药与认知失误之间存在联系。
