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聚焦结直肠腺瘤——我们日常实践中结肠和直肠癌前病变及状况的治疗可能性

[Focus on colorectal adenomas--therapeutic possibilities in precancerous changes and conditions of the colon and rectum in our daily practice]].

作者信息

Popovits József, Rosta Ildikó

机构信息

Albert Schweitzer Kórház, Endoszkópos Laboratórium, Hatvan.

出版信息

Orv Hetil. 2003 Aug 31;144(35):1707-11.

PMID:14533351
Abstract

The health government and also the professionals except the new screening test programme to put a stop the increasing number of colon and rectum cancer diseases, which have caused high mortality in Hungary. Believe in the success of this programme the authors give a short overview about the precancer status and alterations of the large bowel, focusing on colorectal adenoma. In particular, the pathological anatomy, symptomatology, diagnostics, therapy, treatment and prevention possibilities of adenomas are described in details. There were 3419 total colonoscopies carried out in the Laboratory of Endoscopy in Albert Schweitzer General Hospital of Hatvan between 31st January 1991 and 31st December 2001. All patients had bowel motility problems, abdominal pains, bloody stools or change of bowel movement habit. 941 large bowel polyps were diagnosed at 628 patient. 821 of them were removed with endoscopic polypectomy, 11 with mucosectomy, 43 with piecemeal polypectomy and 20 with surgical interventions. 38 carcinoma in situ and 94 serious dysplasia alteration were removed. After the endoscopical therapeutical interventions 5 complications were detected and one patient died. There were no complications after the surgical interventions. They analyse their patients in base of the polyps place, shape, number and histological structure of alterations, level of dysplasia and the type of interventions. It is confirmed that the total colonoscopy is the most adaptable method for examining the large bowel, and endoscopic polypectomy is the most efficient colorectal cancer preventing method, which could only be realized with the successful interdisciplinary cooperation of the gastroenterologist, the surgeon, the pathologist and radiologist.

摘要

卫生部门以及专业人士期望新的筛查测试项目能够遏制匈牙利结肠癌和直肠癌病例不断增加的趋势,这类癌症已导致了很高的死亡率。基于对该项目成功的信心,作者简要概述了大肠的癌前状态及病变,重点是结直肠腺瘤。特别详细描述了腺瘤的病理解剖、症状学、诊断、治疗及预防方法。1991年1月31日至2001年12月31日期间,哈特万市阿尔伯特·施韦策尔综合医院内镜检查实验室共进行了3419例全结肠镜检查。所有患者均有肠道蠕动问题、腹痛、便血或排便习惯改变。在628例患者中诊断出941个大肠息肉。其中821个通过内镜息肉切除术切除,11个通过黏膜切除术切除,43个通过分次息肉切除术切除,20个通过手术干预切除。切除了38例原位癌和94例重度发育异常病变。内镜治疗干预后发现5例并发症,1例患者死亡。手术干预后无并发症。他们根据息肉的位置、形状、数量、病变的组织学结构、发育异常程度及干预类型对患者进行分析。证实全结肠镜检查是检查大肠最适用的方法,内镜息肉切除术是预防结直肠癌最有效的方法,而这只有通过胃肠病学家、外科医生、病理学家和放射科医生成功的跨学科合作才能实现。

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[Focus on colorectal adenomas--therapeutic possibilities in precancerous changes and conditions of the colon and rectum in our daily practice]].聚焦结直肠腺瘤——我们日常实践中结肠和直肠癌前病变及状况的治疗可能性
Orv Hetil. 2003 Aug 31;144(35):1707-11.
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