Kovacić Vedran, Sain Milenka, Vukman Valentina
Centar za turisticku i domicilnu hemodijalizu, Dom zdravlja Trogir, A. Stepinca 17, 21220 Trogir.
Lijec Vjesn. 2003 May-Jun;125(5-6):156-8.
Patients on chronic haemodialysis (PCHD) respond less well to vaccination with recombinant hepatitis B virus superficial antigen (HbsAg) because of immunity disorders in uraemic patients. Today many schemes and vaccination modification for nonresponding PCHD are proposed. The reaction on vaccination with HbsAg is weaker in those PCHD who had diabetes, older age and insufficient nutritive parameters. In those patients some alternative schemes of vaccinating for nonrespondering PCHD must be considered, especially one of the proposed intradermal ways of vaccine inoculation.
由于尿毒症患者存在免疫紊乱，慢性血液透析患者（PCHD）对重组乙型肝炎病毒表面抗原（HbsAg）疫苗接种的反应较差。如今，针对无反应的PCHD患者提出了许多方案和疫苗接种调整方法。患有糖尿病、年龄较大且营养参数不足的PCHD患者对HbsAg疫苗接种的反应较弱。对于这些无反应的PCHD患者，必须考虑一些替代的疫苗接种方案，尤其是一种提议的皮内接种疫苗的方法。
