Tobi H, van den Berg P B, Brouwers J R, de Jong-van den Berg L T
Groningen University Institute for Drug Exploration, afd. Sociale Farmacie, Farmaco-epidemiologie en Farmacotherapie, Antonius Deusinglaan 1, 9713 AV Groningen.
Ned Tijdschr Geneeskd. 2003 Sep 20;147(38):1853-5.
To describe the use of hormone replacement therapy (HRT) and oral contraceptives (OC) among women in the Netherlands in the 45 to 69 years age group during the year 2002.
Descriptive.
Pharmaceutical data on 42,032 women who were in the 45-69 years age group on 31 December 2002 was selected from the InterAction database, a collection of community pharmacy data from the north of the Netherlands. The duration of the therapy was investigated for women who had received at least one HRT or OC prescription in 2002.
Oral contraceptives were used by 11.3% of women aged 50-54 years and 1.8% of women aged 55-59 years. The prevalence of HRT ranged from 6.0% to 11.7% depending on age. Of these users (n = 3885) 28.6% used an oestrogen-progestagen preparation. A treatment period of more than one year was found in 62.3% of women aged 45-49 years and 82.6% of women aged 55-59 years. In particular, preparations containing just oestrogen had been used for a longer period; 43.4% had used these for more than 5 years.
More than half of the women who used HRT had done so for more than one year.
描述2002年荷兰45至69岁年龄段女性使用激素替代疗法（HRT）和口服避孕药（OC）的情况。
描述性研究。
从InterAction数据库中选取了2002年12月31日年龄在45 - 69岁之间的42,032名女性的药品数据，该数据库收集了荷兰北部社区药房的数据。对2002年至少接受过一次HRT或OC处方的女性的治疗持续时间进行了调查。
50 - 54岁女性中11.3%使用口服避孕药，55 - 59岁女性中1.8%使用口服避孕药。HRT的患病率因年龄而异，范围在6.0%至11.7%之间。在这些使用者中（n = 3885），28.6%使用雌激素 - 孕激素制剂。45 - 49岁女性中有62.3%、55 - 59岁女性中有82.6%的治疗期超过一年。特别是，仅含雌激素的制剂使用时间更长；43.4%的人使用这些制剂超过5年。
使用HRT的女性中，超过一半的人使用时间超过一年。
