Shmerling M D, Buzueva I I, Korostyshevskaia I M, Lazarev V A, Maksimov V F, Filiushina E E, Markel' A L, Iakobson G S
Morfologiia. 2005;128(4):85-90.
In rats with inherited stress-induced arterial hypertension (ISIAH strain), myocardium, adrenal gland, and renal glomerular apparatus were studied at different periods of postnatal ontogenesis (3 weeks and 6 months) to assess the influence of the changed conditions of nursing on the development of a hypertensive status and structural-functional characteristics of target organs. It was demonstrated that nursing of rats by foster normotensive Wistar females exerted a modulating influence upon the realization of stress-determined program of arterial hypertension development, seemingly delaying it and alleviating the negative consequences in respect to the target organs, through increased effectiveness of recruitment of adaptive-compensatory organism reserves, however, on the whole, it did not interrupt this program.
在患有遗传性应激诱导性动脉高血压的大鼠（ISIAH品系）中，研究了出生后不同发育阶段（3周和6个月）的心肌、肾上腺和肾小球装置，以评估护理条件变化对高血压状态发展以及靶器官结构功能特征的影响。结果表明，由正常血压的Wistar雌性代孕大鼠哺育，对动脉高血压发展的应激决定程序的实现具有调节作用，似乎延迟了该程序，并通过提高机体适应性补偿储备的募集效率减轻了对靶器官的负面影响，然而，总体而言，并没有中断这一程序。
