Samadi Daniel S, Hockstein Neil G, Tom Lawrence W C
Division of Otolaryngology, The Children's Hospital of Philadelphia, Pennsylvania 1904-4399, USA.
Ann Otol Rhinol Laryngol. 2003 Sep;112(9 Pt 1):813-6. doi: 10.1177/000348940311200912.
Castleman's disease (CD) is a rare, benign lymphoepithelial disease of unknown cause that presents most commonly in the mediastinum. There are 2 histologic types of CD: the hyaline vascular type and the plasma cell type. In the head and neck, 98% of these lesions are of the hyaline vascular type. The differential diagnosis of CD includes reactive lymphadenopathy, lymphoproliferative disorders, lymph node metastasis, and other conditions. Approximately 80 cases of CD have been reported in children; head and neck involvement in children is extremely rare. A case of a child with intraparotid CD is presented; the clinical course, histopathologic presentation, radiographic findings, and management of CD are reviewed.
卡斯特曼病（CD）是一种病因不明的罕见良性淋巴上皮疾病，最常见于纵隔。CD有两种组织学类型：透明血管型和浆细胞型。在头颈部，这些病变的98%为透明血管型。CD的鉴别诊断包括反应性淋巴结病、淋巴增殖性疾病、淋巴结转移及其他情况。儿童中报道的CD病例约有80例；儿童头颈部受累极为罕见。本文报告一例腮腺内CD患儿病例；并对CD的临床病程、组织病理学表现、影像学检查结果及治疗进行综述。
