Uemura Koichi, Sorimachi Yoshihide, Yashiki Mikio, Yoshida Ken-ichi
Department of Forensic Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.
J Forensic Sci. 2003 Sep;48(5):1179-81.
We report on two cases of simultaneous administration of methamphetamine (MAP) and morphine (MOR) with hyperthermia. The blood levels of MAP and MOR were toxic and putatively lethal, respectively, although hyperthermia is a known cause of intoxication due to MAP rather than MOR. In Japan, MAP is the most predominant cause of drug intoxication. The presented cases suggest that MOR may exert synergistic effect on hyperthermia due to the MAP intoxication, together with experimental findings.
我们报告了两例同时服用甲基苯丙胺（MAP）和吗啡（MOR）并伴有高热的病例。MAP和MOR的血药浓度分别具有毒性且可能致死，尽管高热是已知的由MAP而非MOR导致中毒的原因。在日本，MAP是药物中毒最主要的原因。所呈现的病例表明，MOR可能会与实验结果一起，对MAP中毒引起的高热产生协同作用。
