Krause W, Bohring C, Gueth A, Hörster S, Krisp A, Skrzypek J
Department of Andrology, School of Medicine, Philipp Universität, Marburg, Germany.
Andrologia. 2003 Oct;35(5):279-82.
Leucocytospermia is considered to be a sign of male accessory gland inflammation. The leucocytes in semen are mainly polymorphonuclear neutrophilic granulocytes. Leucocytospermia is not associated with the presence of bacteria and antibiotic treatment does not significantly lower the extent of leucocytospermia. A higher frequency of elevated herpes simplex antibodies titres were found in men with leucocytospermia. The concentration of inflammatory cytokines, interleukin-6 and -8, is closely correlated with the number of leucocytes. Their determination does not provide additional information. Reactive oxygen species (ROS) are generated at least in part by seminal leucocytes in response to stimulating factors. Purified leucocytes produce high levels of ROS. The determination of ROS appears to represent a parameter of functional activity of leucocytes. The role of chlamydiae in male accessory gland infection is unclear. Their determination in semen by DNA amplification and by immunological tests does not provide reliable results.
白细胞精子症被认为是男性附属腺炎症的一个迹象。精液中的白细胞主要是多形核嗜中性粒细胞。白细胞精子症与细菌的存在无关，抗生素治疗也不会显著降低白细胞精子症的程度。在白细胞精子症患者中发现单纯疱疹抗体滴度升高的频率更高。炎性细胞因子白细胞介素-6和-8的浓度与白细胞数量密切相关。对它们的测定并不能提供额外信息。活性氧（ROS）至少部分是由精液中的白细胞对刺激因子作出反应而产生的。纯化的白细胞会产生高水平的ROS。ROS的测定似乎代表了白细胞功能活性的一个参数。衣原体在男性附属腺感染中的作用尚不清楚。通过DNA扩增和免疫测试在精液中对它们的测定并不能提供可靠结果。
