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[铅暴露工人的发病率——流行病学研究综述]

[Morbidity among workers exposed to lead--review of epidemiological studies].

作者信息

Hanke W, Szczenia-Dabrowska N

机构信息

Zakładu Epidemiologii i Statystyki Instytutu Medycyny Pracy.

出版信息

Med Pr. 1992;43(4):321-8.

PMID:1453949
Abstract

The paper presents a review of morality studies for workers occupationally exposed to lead. The authors highlighted the limitations which most of the reviewed analyses suffer from and which are due mainly to incomplete characteristics of the exposure in question. As follows from the results of morality studies carried out so far, lead-exposed workers are subject to an increased risk of death from stomach and lung cancer, though the epidemiologic evidence for the latter is not quite explicit. The single reports on the risk of cerebrovascular diseases probably concerns only the high-level exposure. Relatively best documented is the death risk due to nephritis. The authors believe that further research is necessary in order to evaluate delayed health effects of chronic exposure to lead.

摘要

本文对职业性接触铅的工人的死亡率研究进行了综述。作者强调了大多数所综述的分析存在的局限性,这些局限性主要归因于所讨论的接触情况特征不完整。根据迄今为止进行的死亡率研究结果,接触铅的工人患胃癌和肺癌死亡的风险增加,尽管后者的流行病学证据并不十分明确。关于脑血管疾病风险的个别报告可能仅涉及高剂量接触。记录相对最充分的是肾炎导致的死亡风险。作者认为,有必要进行进一步研究,以评估慢性接触铅对健康的延迟影响。

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