Ricketts A P, Dirlam J P, Shively J E
Central Research Division, Pfizer Inc, Groton, Connecticut 06340.
Poult Sci. 1992 Oct;71(10):1626-30. doi: 10.3382/ps.0711626.
The anticoccidial activity of the ionophore CP-82,009 against laboratory isolates of four major species of poultry Eimeria was investigated. Parameters of anticoccidial efficacy that were evaluated were control of lesions and weight suppression. At 4 and 5 ppm, CP-82,009 demonstrated broad-spectrum anticoccidial efficacy in battery trials that was equivalent to reference commercial ionophores. When CP-82,009 was fed to uninfected broiler chickens at efficacious dose levels, growth rate and feed efficiency were found to be equivalent to commercial agents over a 21-day period in batteries and over a 49-day period in floor pens. From the present studies, it appears that CP-82,009 is an efficacious anticoccidial that is well tolerated by chickens, and that it ranks among the most potent anticoccidial ionophores described to date.
研究了离子载体CP - 82,009对四种主要家禽艾美耳球虫实验室分离株的抗球虫活性。评估的抗球虫效力参数包括病变控制和体重抑制。在4 ppm和5 ppm时，CP - 82,009在笼养试验中表现出广谱抗球虫效力，与参考商业离子载体相当。当以有效剂量水平将CP - 82,009喂给未感染的肉鸡时，发现在笼养中21天期间以及在地面围栏中49天期间，其生长速率和饲料效率与商业制剂相当。从目前的研究来看，CP - 82,009似乎是一种有效的抗球虫药，鸡对其耐受性良好，并且它是迄今为止描述的最有效的抗球虫离子载体之一。
