Buckett William M
Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montréal, Québec, Canada.
Fertil Steril. 2003 Oct;80(4):1037-41. doi: 10.1016/s0015-0282(03)01015-x.
To determine the relative efficacy of ultrasound-guided embryo transfer and embryo transfer by clinical touch alone.
Systematic review and meta-analysis of randomized, controlled trials comparing ultrasound-guided embryo transfer with embryo transfer by clinical touch alone.
Infertility centers providing treatment with in vitro fertilization/embryo transfer.
PATIENT(S): Women undergoing embryo transfer.
INTERVENTION(S): Embryo transfer with or without transabdominal ultrasound guidance.
MAIN OUTCOME MEASURE(S): Clinical pregnancy rate and embryo implantation rate.
RESULT(S): A total of eight prospective controlled trials were identified. Of these studies, four were nonrandomized or quasi-randomized and four were genuinely randomized. Meta-analysis demonstrated a significantly increased chance of clinical pregnancy following ultrasound-guided embryo transfer in all studies and in the genuinely randomized subgroup. The embryo implantation rate was also significantly increased following ultrasound-guided embryo transfer.
CONCLUSION(S): Ultrasound-guided embryo transfer significantly increases the chance of clinical pregnancy and significantly increases the embryo implantation rate.
确定超声引导下胚胎移植与单纯临床触诊胚胎移植的相对疗效。
对比较超声引导下胚胎移植与单纯临床触诊胚胎移植的随机对照试验进行系统评价和荟萃分析。
提供体外受精/胚胎移植治疗的不孕不育中心。
接受胚胎移植的女性。
有或无经腹超声引导的胚胎移植。
临床妊娠率和胚胎着床率。
共纳入8项前瞻性对照试验。其中，4项为非随机或半随机试验，4项为真正的随机试验。荟萃分析表明，在所有研究以及真正随机分组的亚组中，超声引导下胚胎移植后临床妊娠的几率显著增加。超声引导下胚胎移植后的胚胎着床率也显著提高。
超声引导下胚胎移植显著增加临床妊娠几率，并显著提高胚胎着床率。
