Hallioglu Olgu, Dilber Embiya, Celiker Alpay
Department of Pediatrics, Section of Pediatric Cardiology, Hacettepe University, Ankara, Turkey.
Am J Cardiol. 2003 Oct 15;92(8):1007-9. doi: 10.1016/s0002-9149(03)00991-3.
Both aerosolized and intravenous infusion of iloprost caused a significant decrease in mean pulmonary artery pressure and pulmonary vascular resistance. Although intravenous infusion caused a large decrease in mean systemic arterial pressure, this was only slightly affected by aerosolized iloprost. Aerosolized iloprost caused a significant decrease in the pulmonary-to-systemic vascular resistance ratio; however, intravenous infusion did not cause a prominent decrease in this ratio.
雾化吸入和静脉输注伊洛前列素均导致平均肺动脉压和肺血管阻力显著降低。虽然静脉输注导致平均体循环动脉压大幅下降，但雾化吸入伊洛前列素对此影响较小。雾化吸入伊洛前列素导致肺循环与体循环血管阻力比值显著降低；然而，静脉输注并未使该比值显著降低。
