Guille James T, Betz Randal R, Balsara Rohinton K, Mulcahey M J, D'Andrea Linda P, Clements David H
A.I. duPont Hospital for Children, Wilmington, Delaware, USA.
Spine (Phila Pa 1976). 2003 Oct 15;28(20):S266-74. doi: 10.1097/01.BRS.0000092485.40061.ED.
Before-after intervention study of a fusionless surgical technique to correct scoliosis secondary to spinal cord injury or myelodysplasia in children and adolescents.
To determine the feasibility, safety, and utility of a fusionless treatment option for paralytic scoliosis. Once determined, these data could then be applied to develop the application of this operation for patients with other types of scoliosis, such as idiopathic.
The optimal operative treatment for paralytic scoliosis remains to be determined. An ideal procedure would correct the deformity and stop the progression of scoliosis while maintaining mobility of the spine. This latter fact is important, especially for patients who rely heavily on use of trunk mobility for function.
Fourteen patients with scoliosis secondary to spinal cord injury or myelodysplasia underwent a fusionless vertebral body wedge osteotomy procedure. Feasibility was analyzed by the ability to correct the scoliosis with the osteotomies and preserve mobility. Safety was reported by estimated blood loss, neurologic stability, and complications. Utility was reported by radiographic evidence of arrested curve progression and maintenance of spinal mobility.
All 14 patients successfully underwent surgery to insert the wedge-rod system, with an average initial correction of 86% (range 66%-108%). The average estimated blood loss was 1050 cc (range 300-2000 cc). There were no major complications, and no changes in spasticity, bowel or bladder patterns, or motor/sensory levels. There was no case of nonunion at the osteotomy sites. At mean follow-up of 15 months (6-29 months), 10 patients had an improvement in their Cobb magnitude, 1 patient was within 5 degrees of their initial curve, 1 patient had a worse Cobb magnitude, and in 2 patients, the curve direction reversed but still measured less than the preoperative Cobb measurement. Spinal mobility was retained in all patients, as demonstrated on side-bending radiographs.
The vertebral wedge osteotomy procedure appears to be a potential option for the treatment of paralytic scoliosis. The procedure was feasible and safely performed in these 14 patients, with spinal mobility maintained. There were no nonunions. The efficacy of the procedure is still not known, as is for which patients the procedure is indicated and timing of the operation. Long-term follow-up (to skeletal maturity) is needed. Only six of the patients are currently skeletally mature, and more numbers are needed to determine efficacy in this group.
对一种用于矫正儿童和青少年脊髓损伤或脊髓发育不良继发脊柱侧弯的非融合手术技术进行前后干预研究。
确定麻痹性脊柱侧弯非融合治疗方案的可行性、安全性和实用性。一旦确定这些数据,就可应用于将该手术应用于其他类型脊柱侧弯患者,如特发性脊柱侧弯患者。
麻痹性脊柱侧弯的最佳手术治疗方法仍有待确定。理想的手术应能矫正畸形并阻止脊柱侧弯进展,同时保持脊柱的活动度。后一点很重要,尤其是对于严重依赖躯干活动功能的患者。
14例脊髓损伤或脊髓发育不良继发脊柱侧弯的患者接受了非融合椎体楔形截骨手术。通过截骨矫正脊柱侧弯并保留活动度的能力来分析可行性。通过估计失血量、神经稳定性和并发症来报告安全性。通过曲线进展停止和脊柱活动度维持的影像学证据来报告实用性。
所有14例患者均成功接受了楔形棒系统植入手术,平均初始矫正率为86%(范围66%-108%)。平均估计失血量为1050毫升(范围300-2000毫升)。无重大并发症,痉挛、肠道或膀胱功能模式或运动/感觉水平均无变化。截骨部位无骨不连病例。平均随访15个月(6-29个月)时,10例患者的Cobb角改善,1例患者的Cobb角与初始曲线相差5度以内,1例患者的Cobb角变差,2例患者的曲线方向反转但仍小于术前Cobb测量值。如侧弯X线片所示,所有患者的脊柱活动度均得以保留。
椎体楔形截骨手术似乎是治疗麻痹性脊柱侧弯的一种潜在选择。该手术在这14例患者中可行且安全,脊柱活动度得以维持。无骨不连情况。该手术的疗效以及适用于哪些患者和手术时机仍不清楚。需要长期随访(至骨骼成熟)。目前只有6例患者骨骼成熟,需要更多病例数来确定该组患者的疗效。