Bone and Joint Clinic of Baton Rouge, Baton Rouge, LA, USA.
Spine (Phila Pa 1976). 2010 Feb 15;35(4):403-10. doi: 10.1097/BRS.0b013e3181c3e89a.
Pre-post intervention study using outcome measure design.
To evaluate the clinical efficacy and functional impact of a fusionless treatment for paralytic scoliosis at 2-year follow-up.
It has been shown that 67% of pediatric patients with progressive paralytic scoliosis require spinal fusion to correct the curve. However, maintenance of spinal flexibility, motion, and potential growth is desirable.
Fourteen patients with scoliosis secondary to spinal cord injury or myelodysplasia underwent a fusionless vertebral wedge osteotomy. Thirteen patients were available for minimum 2-year follow-up, using standard scoliosis radiographs. The functional impact of the procedure was evaluated using the Pediatric Outcomes Data Collection Instrument (PODCI), the Functional Independence Measure (FIM), and the Canadian Occupational Performance Measure (COPM).
At a minimum 2-year follow-up, 10 patients of 13 (77%) had improvement of greater than 5 degrees in their coronal Cobb angle. Two (15%) patients' curves measured the same (+/-5 degrees). One patient's curve had worsened by 12 degrees as compared to the preoperative Cobb angle. The overall average correction of the 13 patients was 56.1%. Two patients required fusion with an average delay to fusion of 30 months. At current follow-up, range of motion across the treated levels averaged 43 degrees (range 8 degrees to 103 degrees). The FIM showed no changes pre to post, and the PODCI scores showed some increases at 2-year follow-up. Clinical and statistical improvement in performance and satisfaction scores was seen pre to post on the Canadian Occupational Performance Measure.
Vertebral wedge osteotomy is potentially an effective treatment option for paralytic scoliosis. At 2-year follow-up, there was no loss of function as measured by the PODCI and FIM, and there was improvement in the COPM. Cobb angle measurements were either improved or maintained in 12 of 13 patients. Although 2 patients required fusion, they had an average of 2.5 years of subsequent growth before surgery.
采用结局测量设计的前后干预研究。
在 2 年随访时评估无融合治疗对麻痹性脊柱侧凸的临床疗效和功能影响。
已经表明,67%的进展性麻痹性脊柱侧凸患儿需要脊柱融合来矫正脊柱侧凸。然而,维持脊柱灵活性、运动能力和潜在生长是理想的。
14 例脊髓损伤或脊髓发育不良引起的脊柱侧凸患者接受了无融合性椎体楔形截骨术。13 例患者获得了至少 2 年的随访,使用标准的脊柱侧凸 X 线片。通过使用儿科结局数据采集工具(PODCI)、功能独立性量表(FIM)和加拿大职业表现量表(COPM)来评估手术的功能影响。
在至少 2 年的随访中,13 例患者中有 10 例(77%)的冠状 Cobb 角改善大于 5 度。2 例(15%)患者的曲线测量结果相同(+/-5 度)。1 例患者的曲线与术前 Cobb 角相比恶化了 12 度。13 例患者的总体平均矫正率为 56.1%。2 例患者需要融合,平均延迟 30 个月进行融合。目前的随访中,治疗水平的活动范围平均为 43 度(范围 8 度至 103 度)。FIM 在术前和术后没有变化,PODCI 评分在 2 年随访时显示出一些增加。在加拿大职业表现量表上,术前和术后的表现和满意度评分都有临床和统计学上的改善。
椎体楔形截骨术是治疗麻痹性脊柱侧凸的潜在有效治疗选择。在 2 年随访时,PODCI 和 FIM 测量的功能没有丧失,COPM 有所改善。13 例患者中有 12 例的 Cobb 角测量值得到改善或保持不变。尽管 2 例患者需要融合,但他们在手术前有平均 2.5 年的后续生长时间。