在结直肠癌患者确诊时就与他们讨论基因检测是否可行？一项试点研究。
Is it acceptable to approach colorectal cancer patients at diagnosis to discuss genetic testing? A pilot study.
作者信息
Porteous M, Dunckley M, Appleton S, Catt S, Dunlop M, Campbell H, Cull A
机构信息
Department of Clinical Genetics, Molecular Medicine Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK.
出版信息
Br J Cancer. 2003 Oct 20;89(8):1400-2. doi: 10.1038/sj.bjc.6601332.
Abstract
In this pilot study, the acceptability of approaching 111 newly diagnosed colorectal cancer patients with the offer of genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC) was assessed. A total of 78% of participants found it highly acceptable to have the information about HNPCC brought to their attention at that time.
摘要
在这项试点研究中，评估了向111名新诊断出的结直肠癌患者提供遗传性非息肉病性结直肠癌（HNPCC）基因检测的可接受性。共有78%的参与者认为在那个时候让他们了解HNPCC的信息是非常可以接受的。
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Comprehensive genetic counseling for families at risk for HNPCC: impact on distress and perceptions.对遗传性非息肉病性结直肠癌（HNPCC）风险家庭的全面遗传咨询：对痛苦和认知的影响。
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