Apostolopoulos Kostas, Ferekidis Eleftherios
Department of Otolaryngology, General State Hospital of Kalamata, Kalamata, Greece.
ORL J Otorhinolaryngol Relat Spec. 2003 Jul-Aug;65(4):235-7. doi: 10.1159/000073123.
We describe a rare case of an extensive primary cranial Ewing's sarcoma located in the greater wing of the sphenoid bone with extension to the orbit, the endocranium, the parapharyngeal and infratemporal space. The patient presented with diplopia, anosmia and prolapse of the left eye. He was given chemo- and radiotherapy and was free of symptoms on re-examination 1.5 years later. The prognosis of Ewing's sarcoma in the absence of surgery is uncertain, but prompt treatment appears to have a satisfactory therapeutic outcome. In the future, more cases should be studied in order to investigate the biological behaviour of a primary cranial Ewing's sarcoma.
我们描述了一例罕见的广泛性原发性颅骨尤因肉瘤病例，肿瘤位于蝶骨大翼，累及眼眶、颅内膜、咽旁间隙和颞下间隙。患者出现复视、嗅觉丧失和左眼突出。给予化疗和放疗，1.5年后复查时无症状。尤因肉瘤在未行手术治疗的情况下预后尚不确定，但及时治疗似乎有令人满意的治疗效果。未来，应研究更多病例以探讨原发性颅骨尤因肉瘤的生物学行为。
