Cutner A, Moscoso G, Cardozo L, Driver M, Cooper D
Department of Obstetrics and Gynaecology, King's College Hospital, London, England.
Anat Rec. 1992 Dec;234(4):568-74. doi: 10.1002/ar.1092340412.
Normal development of the human lower urinary tract was studied between the 14th and 20th week of gestation using 3 modes of fixation. Fixation by direct distension provides a high degree of reproducibility of parameters used to study the growth of the fetal bladder. Using this method, fetuses ranging from 12 to 21 weeks gestation were studied. Results obtained demonstrate that the length of the bladder, the inter-ureteric distance, and the distance between the apex of the trigone and the distal tip of the urethra occur in a linear mode. Furthermore, the rate of growth of the male urethra was evidently higher when compared to that of the female from the 12th week of gestation. Data from this work can be used for a more accurate assessment of cases with abnormal lower urinary tract development.
利用3种固定方法，对妊娠第14至20周的人类下尿路正常发育进行了研究。通过直接扩张进行固定，可为用于研究胎儿膀胱生长的参数提供高度的可重复性。采用该方法，对妊娠12至21周的胎儿进行了研究。获得的结果表明，膀胱长度、输尿管间距离以及膀胱三角顶点与尿道远端之间的距离呈线性模式。此外，从妊娠第12周起，男性尿道的生长速率明显高于女性。这项研究的数据可用于更准确地评估下尿路发育异常的病例。
