Synthesis and biological evaluation of beta-D-pentofuranonucleoside derivatives of 2-azidoadenine and 6-azidopurines.
作者信息
Mathé Christophe, Lioux Thierry, Gosselin Gilles
机构信息
Laboratoire de Chimie Organique Biomoléculaire de Synthèse, UMR 5625 CNRS-Université Montpellier II, Montpellier, France.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):605-9. doi: 10.1081/NCN-120021964.
PMID:14565237
Abstract
Beta-D-pentofuranonucleoside derivatives of 2-azidoadenine and 6-azidopurines have been synthesized. The azido-tetrazolo tautomerism observed on such nucleoside analogues has been studied. The compounds were tested for their activity against HIV and HBV but they did not show significant antiviral effect.
摘要
Zotero 插件