• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Properties of triple helices formed by oligonucleotides containing 8-aminopurines.

作者信息

Aviñó A, Frieden M, Morales J C, de la Torre B G, Güimil-García R, Orozco M, González C, Eritja R

机构信息

Instituto de Biologia Molecular de Barcelona, Barcelona, Spain.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):645-8. doi: 10.1081/NCN-120021971.

DOI:10.1081/NCN-120021971
PMID:14565244
Abstract

The synthesis of parallel hairpins carrying 8-aminopurines is described. These hairpins have a high affinity for specific polypyrimidine sequences resulting in the formation of very stable triplexes.

摘要

相似文献

1
Properties of triple helices formed by oligonucleotides containing 8-aminopurines.
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):645-8. doi: 10.1081/NCN-120021971.
2
Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines.由含8-氨基嘌呤的平行链发夹形成的三螺旋的性质。
Nucleic Acids Res. 2002 Jun 15;30(12):2609-19. doi: 10.1093/nar/gkf374.
3
Antiparallel triple helices. Structural characteristics and stabilization by 8-amino derivatives.反平行三螺旋。结构特征及8-氨基衍生物的稳定作用
J Am Chem Soc. 2003 Dec 24;125(51):16127-38. doi: 10.1021/ja035039t.
4
Synthesis and studies of modified oligonucleotides-directed triple helix formation at the purine-pyrimidine interrupted site.嘌呤 - 嘧啶间断位点处修饰寡核苷酸导向三链螺旋形成的合成与研究
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1277-80. doi: 10.1081/NCN-120022945.
5
[Cyclic oligonucleotides. III. Ability to form triplexes with oligodeoxyribonucleotides, consisting of mixed pyrimidine and purine sequences].
Mol Biol (Mosk). 1997 Sep-Oct;31(5):839-46.
6
Chemical modification of pyrimidine TFOs: effect on i-motif and triple helix formation.嘧啶类三链体形成寡核苷酸的化学修饰:对i-基序和三链螺旋形成的影响。
Arch Biochem Biophys. 2000 Sep 1;381(1):153-63. doi: 10.1006/abbi.2000.1934.
7
Parallel double stranded helices and the tertiary structure of nucleic acids.平行双链螺旋与核酸的三级结构。
Nucleic Acids Symp Ser. 1991(24):167-8.
8
Synthesis and evaluation of oligonucleotides incorporating novel artificial nucleobases for the selective formation of non-natural type triplexes.用于选择性形成非天然型三链体的含新型人工碱基的寡核苷酸的合成与评估。
Nucleic Acids Symp Ser. 1997(37):33-4.
9
Evidence for a DNA triplex in a recombination-like motif: I. Recognition of Watson-Crick base pairs by natural bases in a high-stability triplex.类重组基序中DNA三链体的证据:I. 高稳定性三链体中天然碱基对沃森-克里克碱基对的识别
J Mol Recognit. 2001 Mar-Apr;14(2):122-39. doi: 10.1002/jmr.528.
10
Parallel-stranded hairpins containing 8-aminopurines. Novel efficient probes for triple-helix formation.
Bioorg Med Chem Lett. 2001 Jul 9;11(13):1761-3. doi: 10.1016/s0960-894x(01)00295-5.

引用本文的文献

1
Binding of HIV-1 TAR mRNA to a peptide nucleic acid oligomer and its conjugates with metal-ion-binding multidentate ligands.HIV-1 TAR mRNA与肽核酸寡聚物及其与金属离子结合多齿配体的缀合物的结合。
J Biol Inorg Chem. 2009 Feb;14(2):287-300. doi: 10.1007/s00775-008-0448-6. Epub 2008 Nov 18.