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(Z)-(1-氟-2-羟甲基环丙基甲基)嘌呤的合成

Synthesis of (Z)-(1-fluoro-2-hydroxymethylcyclopropylmethyl)purines.

作者信息

Park Ju-Hyun, Lee Young Rang, Chun Moon Woo, Jeong Lak Shin, Lee Chong-Kyo, Kim Hee-Doo

机构信息

College of Pharmacy, Sookmyung Women's University, Yongsangu, Seoul, Korea.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):659-61. doi: 10.1081/NCN-120022605.

DOI:10.1081/NCN-120022605
PMID:14565247
Abstract

(Z)-(1-fluoro-2-hydroxymethylcyclopropylmethyl)purines were designed, synthesized and evaluated their antiviral activity against poliovirus, HSV, and HIV.

摘要

设计、合成了(Z)-(1-氟-2-羟甲基环丙基甲基)嘌呤，并评估了它们对脊髓灰质炎病毒、单纯疱疹病毒和人类免疫缺陷病毒的抗病毒活性。

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