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A facile synthetic method for 3'-alpha-fluoro-2',3'-dideoxyadenosine.

作者信息

Takamatsu Satoshi, Katayama Satoshi, Naito Masaki, Yamashita Keizo, Ineyama Takashi, Izawa Kunisuke

机构信息

AminoScience Laboratories, Ajinomoto Co., Inc., Kawasaki-ku, Kawasaki, Japan.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):711-3. doi: 10.1081/NCN-120022616.

DOI:10.1081/NCN-120022616
PMID:14565260
Abstract

A facile method for the synthesis of 3'-alpha-fluoro-2',3'-dideoxyadenosine (5) has been developed using a novel rearrangement of 3'-beta-bromine to the 2'-beta position during 3'-alpha fluorination.

摘要

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