烯属肽核酸（OPA）。
Olefinic peptide nucleic acid (OPA).
作者信息
Gautschi Daniel, Leumann Christian J
机构信息
Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1211-3. doi: 10.1081/NCN-120022838.
PMID:14565382
Abstract
The olefinic peptide nucleic acid analogues (OPA) monomers containing the bases thymine and adenine were synthesised in 11 steps. Fully modified oligomers containing these units were prepared and their pairing properties assessed by means of UV-melting experiments.
摘要
含有胸腺嘧啶和腺嘌呤碱基的烯烃肽核酸类似物（OPA）单体通过11步合成。制备了含有这些单元的完全修饰的寡聚物，并通过紫外熔解实验评估了它们的配对性质。
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