Russell J J, Sikov M R, Kathren R L
United States Transuranium and Uranium Registries, Washington State University, Richland, WA 99352, USA.
Radiat Prot Dosimetry. 2003;104(3):231-6. doi: 10.1093/oxfordjournals.rpd.a006186.
The placenta and umbilical cord were obtained following a normal live delivery from a volunteer donor who had received an accidental inhalation intake of plutonium 12 years prior to her pregnancy (Case 0777). Her employer estimated the intake to be about 73 Bq Class W plutonium. Based on bioassay results and clearance models in use at that time, they calculated her body content at the beginning of pregnancy to be about 5.6 Bq with an average concentration of approximately 60 mBq kg(-1). The placenta and cord from this pregnancy, along with the placenta and cord from a donor with no known exposure to plutonium (Case 0835), were divided and assayed for plutonium by ultrasensitive fission track analysis at two collaborating laboratories. Placental 239Pu concentration values obtained by the two laboratories for Case 0777 agreed within a factor of 2 and were several-fold greater than for the control, Case 0835, as well as values that had been reported by others for unexposed populations. There was no elevated concentration of plutonium in the umbilical cord from the exposed person. The data yielded values of 0.16 and 0.27 for placental to maternal concentrations (CPl: CM) that were of the same order of magnitude as the value of 0.1 the ICRP calculated for intakes before pregnancy.
胎盘和脐带取自一名志愿捐赠者的正常顺产，该捐赠者在怀孕前12年意外吸入了钚（病例0777）。她的雇主估计吸入量约为73贝克勒尔W级钚。根据当时使用的生物测定结果和清除模型，他们计算出她在怀孕初期的体内钚含量约为5.6贝克勒尔，平均浓度约为60毫贝克勒尔/千克（-1）。此次怀孕的胎盘和脐带，以及一名无已知钚暴露史的捐赠者（病例0835）的胎盘和脐带，被分割后在两个合作实验室通过超灵敏裂变径迹分析测定钚含量。两个实验室针对病例0777获得的胎盘239Pu浓度值相差不超过两倍，且比对照组病例0835以及其他未暴露人群报告的值高出几倍。暴露者脐带中的钚浓度没有升高。数据得出胎盘与母体浓度（CPl: CM）的值分别为0.16和0.27，与国际辐射防护委员会（ICRP）为怀孕前摄入量计算的0.1值处于同一数量级。
