Georgiadis Alexandros L, Suarez José I
Department of Neurology, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
Curr Neurol Neurosci Rep. 2003 Nov;3(6):524-30. doi: 10.1007/s11910-003-0058-1.
Raised intracranial pressure (ICP) is a major contributor to the mortality of many conditions encountered in a neurologic intensive care unit. Achieving a sustained reduction in ICP in patients with intracranial hypertension remains a challenge. Treatment with hyperosmolar agents is one of the few options that are available, and mannitol is currently the most commonly used agent. However, hypertonic saline solutions have recently emerged as a potentially safer and more efficacious alternative to mannitol.
颅内压升高（ICP）是神经重症监护病房中许多病症致死的主要原因。实现颅内高压患者的颅内压持续降低仍然是一项挑战。使用高渗药物治疗是现有的少数选择之一，甘露醇是目前最常用的药物。然而，高渗盐溶液最近已成为甘露醇潜在更安全、更有效的替代品。
