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脉冲持续时间可调的钬激光的实验与临床研究

Experimental and clinical study of a holmium: YAG laser with adjustable pulse duration.

作者信息

Yoshida T, Fujimura K, Yamazaki T, Nogaki J, Okada K

机构信息

Department of Urology, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Aktuelle Urol. 2003 Jul;34(4):276-8. doi: 10.1055/s-2003-41617.

DOI:10.1055/s-2003-41617
PMID:14566685
Abstract

BACKGROUND

The holmium:YAG laser is used for treatment of urolithiasis, transurethral laser ablation for benign prostate hypertrophy and bladder tumor. The pulse duration was fixed in the previous Ho:YAG laser systems. We have evaluated more practical pulse durations to disintegrate the stone. The SPHINX Ho40 (Heraeus Corporation) can change the pulse duration freely in the range from 150 microsec. to 800 microsec.

MATERIALS AND METHODS

  1. We measured the total energy to perforate through stone models at three different pulse durations (150, 300, 600 microsec.). 2) We experimented with the energy of each single pulse and the power of the shock wave. 3) We observed thermogenesis during the lithotripsy for each pulse duration. 4) Disintegration effects of Ho:YAG are compared with other lithotripsy systems in clinical cases.

RESULTS

  1. It was possible that the smallest amount of the total energy went through the fragment at the pulse duration 150 microsec. 2) The maximum amount of energy of the wave is higher when the pulse duration is short. Although the amount of energy was 12.6 V, the amounts of energy at 800 microsec decreased with a pulse duration 150 microsec. to 6.46 V which was about 40 % 3) The highest temperatures achieved when the irradiation of laser was started and finished were compared. The shorter the pulse duration was, the higher was the peak power. The shock wave was also more effective to disintegrate stones on using short pulse durations. 4) The individual clinical success rates are Ho:YAG (85.1 %), Alexandrite (80.6 %) and Lithoclast (74.5 %).
摘要

背景

钬激光用于治疗尿石症、经尿道激光消融治疗良性前列腺增生和膀胱肿瘤。在以往的钬激光系统中,脉冲持续时间是固定的。我们评估了更实用的脉冲持续时间以粉碎结石。SPHINX Ho40(贺利氏公司)可在150微秒至800微秒的范围内自由改变脉冲持续时间。

材料与方法

1)我们在三种不同的脉冲持续时间(150、300、600微秒)下测量穿透结石模型的总能量。2)我们对每个单脉冲的能量和冲击波的功率进行了实验。3)我们观察了每个脉冲持续时间的碎石过程中的产热情况。4)在临床病例中,将钬激光的粉碎效果与其他碎石系统进行比较。

结果

1)在150微秒的脉冲持续时间下,通过碎片的总能量可能最小。2)当脉冲持续时间短时,波的最大能量更高。尽管能量为12.6伏,但在800微秒时的能量随着脉冲持续时间从150微秒降至6.46伏而减少,约为40%。3)比较了开始和结束激光照射时达到的最高温度。脉冲持续时间越短,峰值功率越高。在使用短脉冲持续时间时,冲击波对粉碎结石也更有效。4)个体临床成功率分别为:钬激光(85.1%)、翠绿宝石激光(80.6%)和超声碎石机(74.5%)。

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引用本文的文献

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