Lee Ho, Kang Hyun Wook, Teichman Joel M H, Oh Junghwan, Welch Ashley J
Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital, BHX 630, 50 Blossom Street, Boston, 02114, USA.
Lasers Surg Med. 2006 Jan;38(1):39-51. doi: 10.1002/lsm.20258.
We tested Ho:YAG and Er:YAG laser ablation of human urinary calculi to determine if Er:YAG is a more efficient lithotripsy device.
STUDY DESIGN/MATERIALS AND METHODS: Ablation efficiency of Ho:YAG and Er:YAG lasers was tested at varying energy settings, ranging from the damage threshold to clinical energy setting associated with Ho:YAG laser. Stones of known composition (calcium oxalate monohydrate (COM), cystine, and uric acid (UA)) were irradiated. Crater width, depth, and ablation volumes were determined using an optical coherence tomography (OCT).
For all stones and energy settings, the Er:YAG laser produced deeper craters and larger ablation volumes than Ho:YAG laser. The Ho:YAG laser created wider craters during the multiple pulse process and the shape of craters was irregular.
The Er:YAG laser is more efficient than the Ho:YAG laser for lithotripsy. The deeper craters produced by the Er:YAG laser is attributed to the high absorption of energy at its wavelength.
我们对钬激光（Ho:YAG）和铒激光（Er:YAG）用于人体尿路结石的消融进行了测试，以确定铒激光是否为一种更有效的碎石设备。
研究设计/材料与方法：在从损伤阈值到与钬激光相关的临床能量设置范围内的不同能量设置下，测试钬激光和铒激光的消融效率。对已知成分（一水草酸钙（COM）、胱氨酸和尿酸（UA））的结石进行照射。使用光学相干断层扫描（OCT）确定弹坑宽度、深度和消融体积。
对于所有结石和能量设置，铒激光产生的弹坑比钬激光更深，消融体积更大。钬激光在多脉冲过程中产生的弹坑更宽，且弹坑形状不规则。
铒激光在碎石方面比钬激光更有效。铒激光产生更深弹坑的原因在于其波长处能量的高吸收。
