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宫腔镜治疗宫腔粘连后的生育能力

[Fertility after hysteroscopic treatment of intra-uterine adhesions].

作者信息

Kdous M, Hachicha R, Zhiou F, Ferchiou M, Chaker A, Meriah S

机构信息

Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Aziza-Othmana, 1000 Tunis, Tunisie.

出版信息

Gynecol Obstet Fertil. 2003 May;31(5):422-8. doi: 10.1016/s1297-9589(03)00101-2.

DOI:10.1016/s1297-9589(03)00101-2
PMID:14567119
Abstract

OBJECTIVE

The main aim of the study was to evaluate the efficacy of hysteroscopy in the treatment of intra-uterine adhesions with infertility.

PATIENTS AND METHODS

This retrospective study of patients with uterine synechias treated exclusively hysteroscopically included 120 cases: 109 of them (90.8%) low fertility patients, 110 (91.7%) with menstrual disorders and 2 (1.7%) with no others symptoms. Mean age was 34 years (range: 21-45 years). Operative hysteroscopy was performed in 155 cases including electrosection in 124 cases (80%) and a collapse in 31 cases (20%). A single endoscopic procedure was performed in 96 patients, 2 procedures in 17 patients, 3 in 3 patients and 4 in 4 patients. Mean follow-up was 26.8 months (range: 6-52 months).

RESULTS

Good anatomic results were achieved in 116 patients (96.7%) after 1, 2 or 3 hysteroscopic procedures. We obtained good results in 58.2% of the patients with menstrual disorders. One pregnancy was achieved in 49 of patients (44.9%) including: 35 childbirth, 13 abortions and 1 molar pregnancy.

DISCUSSION AND CONCLUSION

Hysteroscopy, easy procedure, allowing reproducible treatment with low morbidity should be proposed as first intention treatment in all cases with synechia. Fertility prognosis is tightly related to the gravity of synechia and its topography.

摘要

目的

本研究的主要目的是评估宫腔镜检查在治疗伴有不孕症的宫腔粘连中的疗效。

患者与方法

这项对仅接受宫腔镜治疗的子宫粘连患者的回顾性研究纳入了120例患者:其中109例(90.8%)为低生育力患者,110例(91.7%)有月经紊乱,2例(1.7%)无其他症状。平均年龄为34岁(范围:21 - 45岁)。155例患者接受了手术宫腔镜检查,其中124例(80%)进行了电切术,31例(20%)进行了粘连分离术。96例患者进行了单次内镜手术,17例患者进行了2次手术,3例患者进行了3次手术,4例患者进行了4次手术。平均随访时间为26.8个月(范围:6 - 52个月)。

结果

在1、2或3次宫腔镜手术后,116例患者(96.7%)获得了良好的解剖学结果。月经紊乱患者中有58.2%取得了良好效果。49例患者(44.9%)实现了一次妊娠,包括:35例分娩、13例流产和1例葡萄胎妊娠。

讨论与结论

宫腔镜检查操作简便,能进行可重复的治疗且发病率低,应作为所有粘连病例的首选治疗方法。生育预后与粘连的严重程度及其部位密切相关。

相似文献

1
[Fertility after hysteroscopic treatment of intra-uterine adhesions].宫腔镜治疗宫腔粘连后的生育能力
Gynecol Obstet Fertil. 2003 May;31(5):422-8. doi: 10.1016/s1297-9589(03)00101-2.
2
[Hysteroscopic treatment of uterine synechias. A report of 102 cases].[宫腔镜治疗子宫粘连。102例报告]
J Gynecol Obstet Biol Reprod (Paris). 1996;25(1):33-40.
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Hysteroscopic adhesiolysis: efficacy and safety.宫腔镜粘连松解术:疗效与安全性。
Arch Gynecol Obstet. 2016 Aug;294(2):411-6. doi: 10.1007/s00404-016-4107-9. Epub 2016 Apr 29.
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Eur J Obstet Gynecol Reprod Biol. 2015 Oct;193:65-9. doi: 10.1016/j.ejogrb.2015.06.025. Epub 2015 Jul 21.
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Reproductive outcome following hysteroscopic management of intrauterine septum and adhesions.宫腔镜治疗子宫纵隔和粘连后的生殖结局
Hum Reprod. 1995 Oct;10(10):2663-5. doi: 10.1093/oxfordjournals.humrep.a135763.
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Hysteroscopic treatment of intrauterine adhesions is safe and effective in the restoration of normal menstruation and fertility.宫腔镜治疗宫腔粘连在恢复正常月经和生育能力方面安全有效。
Fertil Steril. 1997 Dec;68(6):1141-3. doi: 10.1016/s0015-0282(97)00375-0.
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The nature of intrauterine adhesions following reproductive hysteroscopic surgery as determined by early and late follow-up hysteroscopy: clinical implications.通过早期和晚期随访宫腔镜检查确定的生殖宫腔镜手术后宫腔粘连的性质:临床意义
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Factors That Impact Fertility after Hysteroscopic Adhesiolysis for Intrauterine Adhesions and Amenorrhea: A Retrospective Cohort Study.影响宫腔镜粘连松解术治疗宫腔粘连并闭经后生育能力的因素:一项回顾性队列研究。
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[Fertility after hysteroscopic treatment of intra-uterine adhesions. Gynécol Obstét Fertil 2003;31:422-428].[宫腔镜治疗宫腔粘连后的生育情况。《妇产科与生殖医学》2003年;31卷:422 - 428页]
Gynecol Obstet Fertil. 2003 Dec;31(12):1077-8; author reply 1078-9. doi: 10.1016/j.gyobfe.2003.10.009.

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